Selection of NSAIDs for Osteoarthritis

NSAID Use in United States

NSAID Use on the Rise in the United States

Osteoarthritis

NSAID Use and Selection Important Considerations

Assessment for NSAID GI Toxicity Risk 2009 ACG Guidelines

Cumulative Incidence of a Confirmed Upper Gastrointestinal Event

VIGOR: High-Dose Rofecoxib Increases CV Events*

CNT: Effects of Coxib Therapy on Major Vascular Events and Heart Failure

CNT: Relative Risk for Major Vascular Events, Traditional NSAIDs

2009 American College of Gastroenterology Guidelines Prevention of NSAID-Related Ulcer Complications

Variables Determining NSAID CV Risk

Cyclooxygenase

COX-inhibitor Effects

Variables Determining NSAID CV Risk

NSAIDs Interaction with Low-Dose Aspirin

Naproxen and Low Dose Aspirin

FDA Strengthens NSAID CV Warning

The PRECISION Trial

Common Primary Care Scenarios

Common Primary Care Scenarios Polypharmacy Safeguards

Summary

Abbreviations

Abbreviations (cont)