Treatment of Psoriasis with Mesenchymal Stem Cells

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Presentation transcript:

Treatment of Psoriasis with Mesenchymal Stem Cells Hu Chen, MD, PhD, Jing-Wen Niu, MD, Hong-Mei Ning, MD, PhD, Xin Pan, MD, Xiao-Bin Li, PhD, Yu Li, MD, Dan-Hong Wang, MD, Liang-Ding Hu, MD, Hong-Xia Sheng, MS, Man Xu, MS, Li Zhang, MD, PhD, Bin Zhang, MD, PhD The American Journal of Medicine Volume 129, Issue 3, Pages e13-e14 (March 2016) DOI: 10.1016/j.amjmed.2015.11.001 Copyright © 2016 Elsevier Inc. Terms and Conditions

Figure Clinical images. (A) Patient no. 1: (A1) Pre UC-MSCs infusions: well-defined erythematous plaques with adherent silvery scales symmetrically distributed throughout the body, mainly including the forehead, face, upper chest, abdomen, back, and legs; (A2) Six months after UC-MSCs infusion; (A3) Clearance of psoriasis (12 months after starting UC-MSCs infusion). (B) Patient no. 2: (B1) Pre the first UC-MSCs infusion: drip-like plaques with adherent silvery scales distributed extensively, mainly on extensor aspects of elbows and knees, back, lumbosacral region, and around the umbilicus; (B2) After the third UC-MSCs infusion, the patient's skin turned smooth without any active lesions (the pigmentation was due to the historical steroidal agent). UC-MSCs = umbilical cord-derived mesenchymal stem cells. The American Journal of Medicine 2016 129, e13-e14DOI: (10.1016/j.amjmed.2015.11.001) Copyright © 2016 Elsevier Inc. Terms and Conditions