Tuning the response of the DPI Tuning the response of the DPI. The DPI I/O in HEK‐293T cells measured with luciferase for three synthetic protein pairs (Box 1): DocS‐WT/Coh2 (blue) and the more weakly binding pairs DocS15/Coh2 (green) and Doc102/Coh2 (red); single (gray bars) and dual‐promoter entries are indicated. Tuning the response of the DPI. The DPI I/O in HEK‐293T cells measured with luciferase for three synthetic protein pairs (Box 1): DocS‐WT/Coh2 (blue) and the more weakly binding pairs DocS15/Coh2 (green) and Doc102/Coh2 (red); single (gray bars) and dual‐promoter entries are indicated. Lior Nissim, and Roy H Bar‐Ziv Mol Syst Biol 2010;6:444 © as stated in the article, figure or figure legend