Diet as a Therapy for Irritable Bowel Syndrome: Progress at Last Magnus Simrén Gastroenterology Volume 146, Issue 1, Pages 10-12 (January 2014) DOI: 10.1053/j.gastro.2013.11.027 Copyright © 2014 AGA Institute Terms and Conditions
Figure 1 Proposed mechanisms involved in the generation of gastrointestinal (GI) symptoms after intake of FODMAPs. Several factors affect the absorption of these short-chain carbohydrates in the small intestine. Incomplete absorption of FODMAPs leads to increased water retention through their osmotic activity and to gas production due to fermentation by gas bacteria. This leads to intestinal distension, which together with peripheral and central predisposing factors can generate GI symptoms. Gastroenterology 2014 146, 10-12DOI: (10.1053/j.gastro.2013.11.027) Copyright © 2014 AGA Institute Terms and Conditions