Warm-up Problem: Autosomal Recessive Steve and Linda have a history of cystic fibrosis in their families. Steve is a healthy carrier and Linda is heterozygous. They always wanted a family with three children (make the children any gender you wish). Linda Complete a Pedigree showing these 5 people. Complete a Punnett square for Steve & Linda. What is the probability for having a healthy child? What is the probability that all three children will be healthy? Steve Hh Hh ¾ healthy Steve ¾ healthy Linda ¾ healthy Steve H h 3/4 H Steve HH Hh Key H = healthy h = cystic fibrosis h Hh hh 27/64

Warm-up Problem: Autosomal Dominance Rodney recently tested negative for the FH gene even though his mother and father had FH. Francine recently survived a heart attack at 34 years of age. They have two children who were recently tested negative for the FH gene. Complete a Pedigree showing these 6 people. Complete a Punnett square for Rodney & Francine. What is the probability for having a healthy child? What were the odds of Rodney being born without the FH gene? h Hh Hh H h Steve Hh Hh hh hh Francine Francine Rodney hh Hh 50% hh hh 25% Key H = FH disorder h = healthy

Warm-up Problem: Autosomal Recessive Steve and Linda have a history of cystic fibrosis in their families. Steve is a healthy carrier and Linda is heterozygous. They always wanted a family with three children (make the children any gender you wish). Complete a Pedigree showing these 5 people. Complete a Punnett square for Steve & Linda. What is the probability for having a healthy child? What is the probability that all three children will be healthy?

Warm-up Problem: Autosomal Recessive Steve and Linda have a history of cystic fibrosis in their families. Steve is a healthy carrier and Linda is heterozygous. They always wanted a family with three children (make the children any gender you wish). Complete a Pedigree showing these 5 people. Complete a Punnett square for Steve & Linda. What is the probability for having a healthy child? What is the probability that all three children will be healthy?

Warm-up Problem: Autosomal Dominance Rodney recently tested negative for the FH gene even though his mother and father had FH. Francine recently survived a heart attack at 34 years of age. They have two children who were recently tested negative for the FH gene. Complete a Pedigree showing these 6 people. Complete a Punnett square for Rodney & Francine. What is the probability for having a healthy child? What were the odds of Rodney being born without the FH gene?

Warm-up Problem: Autosomal Dominance Rodney recently tested negative for the FH gene even though his mother and father had FH. Francine recently survived a heart attack at 34 years of age. They have two children who were recently tested negative for the FH gene. Complete a Pedigree showing these 6 people. Complete a Punnett square for Rodney & Francine. What is the probability for having a healthy child? What were the odds of Rodney being born without the FH gene?