Chest Pain and Progressive Miliary Infiltrates in an Elderly Man

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Presentation transcript:

Chest Pain and Progressive Miliary Infiltrates in an Elderly Man Jeffrey B. Rubins, MD, FCCP, Robin Solomon, MD, Thomas Colby, MD, FCCP, Rosemary Kelly, MD, FCCP CHEST Volume 135, Issue 2, Pages 578-582 (February 2009) DOI: 10.1378/chest.07-3002 Copyright © 2009 The American College of Chest Physicians Terms and Conditions

Figure 1 Chest radiograph showing residual infiltrate at the left lung base with slight blunting of the left costophrenic angle, and interstitial nodular markings in both lower lung fields. CHEST 2009 135, 578-582DOI: (10.1378/chest.07-3002) Copyright © 2009 The American College of Chest Physicians Terms and Conditions

Figure 2 Top: Chest CT showing innumerable tiny bilateral pulmonary nodular densities ranging from 1 to 3 mm in diameter, and bilateral calcified pleural plaques. Bottom: Demonstration of bilateral calcified pleural plaques suggesting asbestos-related pleural disease. CHEST 2009 135, 578-582DOI: (10.1378/chest.07-3002) Copyright © 2009 The American College of Chest Physicians Terms and Conditions

Figure 3 Biopsy samples. Top: Low-power image of several nodules of metastatic mesothelioma with intervening normal lung parenchyma, blood vessel, and bronchiole (hematoxylin-eosin, original × 2.5). Center and bottom: Intermediate and high-power fields showing tumor nodules with bland, eosinophilic cells forming occasional gland-like structures (hematoxylin-eosin, original × 10 and original × 40, respectively). CHEST 2009 135, 578-582DOI: (10.1378/chest.07-3002) Copyright © 2009 The American College of Chest Physicians Terms and Conditions