OBSTRUCTIVE SLEEP APNOEA (OSA) IN REGIONAL AND REMOTE INDIGENOUS AUSTRALIANS , Cindy Woods1,2, Kim Usher2, Karen McPherson3, Erik Tikoft3, Graeme Maguire1,4.

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OBSTRUCTIVE SLEEP APNOEA (OSA) IN REGIONAL AND REMOTE INDIGENOUS AUSTRALIANS , Cindy Woods1,2, Kim Usher2, Karen McPherson3, Erik Tikoft3, Graeme Maguire1,4 1College of Medicine and Dentistry, James Cook University (Cairns, QLD, Australia) 2 School of Health, University of New England (Armidale, NSW, Australia) 3Alice Springs Hospital (Alice Springs, NT, Australia), 4Baker IDI (Melbourne, VIC, Australia). BACKGROUND Despite Aboriginal and Torres Strait islander people having increased risk factors for OSA (diabetes, obesity) and AIMS/OBJECTIVES The aim of this study was to compare the use of sleep diagnostic tests, the risks, and cofactors, and outcomes of the care of Indigenous and non-indigenous Australian adults in regional and remote Australia in whom sleep related breathing disorders have been diagnosed. METHODS A retrospective cohort study of 200 sequential subjects: 100 Aboriginal and/or Torres Strait Islander people and 100 non-Indigenous Australians in northern Queensland and Central Australia. Subjects were eighteen years or older with a diagnosed sleep disorder (AHI > 15). Retrospective data collected from patients’ medical records included: demographics; co-morbidities; BMI; fatigue score; referral source and management details for 12 months following diagnosis. Follow up included the number of reviews booked and number of reviews attended. RESULTS DISCUSSION Accessing sleep services is a significant issue for Indigenous and non-Indigenous Australians living in regional and remote communities. Aboriginal and Torres Strait Islanders suffering from sleep disorders are more likely to be; younger, female, obese and have a history of chronic disease. Access to sleep services in these regional and remote communities is poorer than that seen in Australia overall (see Table below), particularly for Aboriginal and Torres Strait Islander people. Reasons for this may include: Population at much lower risk Unlikely, especially in Indigenous Australians with greater obesity and co-morbidities. Accessing other diagnostic services Likely for non-Indigenous Australians but unlikely for Indigenous Australians who rarely access private healthcare. Differing referral patterns Only people perceived likely to be able to attend, afford and/or comply with treatment are referred for diagnostic sleep studies. There is a poorer uptake of treatment following sleep studies in Indigenous Australians. This may occur because: more remote and more limited access to follow-up services cost implications (replacement of machines, masks etc). CONCLUSION Appropriate and more accessible diagnostic and treatment sleep services are required in regional and remote Australia. Further research is required to validate appropriate screening tools and pathways of care especially for Aboriginal and Torres Strait Islander peoples. Subject Characteristics Aboriginal &/or Torres Strait Islander Non-Indigenous Australian Number 100 Age (mean,SD) 47.3 (12.6) 50.7 (12.7) Ethnicity n (%) Aboriginal 86 (43%) - Torres Strait Islander 12 (6%) Aboriginal & Torres Strait Is. 2 (1%) Gender (% female,95% CI) 48.0 (38 - 57) 26.0 (18 - 36)* Location (% very remote,95% CI) 37.9 (28 - 48) 8.4 (4 - 16)* Co-morbidities (%,95% CI) Chronic lung disease 34.0 (25 - 44) 22.2 (15 - 32) Heart disease 28.0 (20 - 38) 13.1 (7- 21)* Chronic kidney disease 14.6 (8 - 23) 2.50(0 - 9)* Peptic ulcer disease 19.8 (12 - 30) 22.80 (14 - 34) Diabetes 51.0 (41 – 61) 24.20 (16 - 34)* Hypertension 72.0 (62 - 81) 39.40 (30 - 50)* Upper Airway Obstruction 9.00 (4 -17) 26.30 (17- 38)* BMI (mean, SD) 40.0 (10.7) 34.9 (10.2)* (%, 95% CI) Underweight <20 Normal 20-25 1.2 (0. 7) 7.1 (3 -15) Overweight 26-30 4.9 (1 - 12) 16.7 (9 - 26) Obese >30 93.8 (86 - 98) 76.2 (66 - 85) ESS (Median,IQR) 10 (7, 15) 10 (6, 15) ESS assessed (%,95% CI) 92.0 (85 - 97) 97.0 (92 - 99) high levels of comorbid associated conditions (chronic non-communicable diseases) there are currently no published data relating to the nature of sleep-related breathing disorders affecting Indigenous adults. Although there is considerable information from metropolitan services regarding diagnostic and management pathways for OSA, there is less information regarding care for Australians living in regional and remote Australia and particularly for Indigenous Australians. ESS – Epworth Sleepiness Score, *p<0.05 Indication for diagnostic sleep study Diagnostic study rates Aboriginal and Torres Strait Islander Non-Indigenous Australian All p value Number of sleep studies/100,000/yr (95% CI) FNQ 44 (32 - 59) 30 (20 - 43) 32 (22 - 45) 0.130 CA 104 (85 - 126) 203 (176 - 233) 163 (139 -190) <0.001 62 (47 - 79) 50 (37 - 66) 52 (39 - 68) 0.298 P Value Number of positive sleep studies/100,000/yr (95% CI) 30 (20-43) 16 (9 -26) 18 (11 - 28) 0.054 73 (57-92) 121 (100 - 144) 101 (82 - 123) 43 (31-58) 28 (19 - 40) 31 (21 - 44) 0.095 Diagnosis and Follow Up Overall Australian rate (2012) 575/100,000/pa FNQ – Far North Queensland, CA – Central Australia Aboriginal &/or Torres Strait Islander Non-Indigenous Australian Time between referral and diagnostic study (Median weeks, IQR) 27.5 (13.0-62.2) 24.9 (11.7-47.6) Diagnosis (%, 95% CI) Obstructive sleep apnoea 98 (93-100) 97 (91-99) Central sleep apnoea 2 (0 - 7) Cheyne Stokes respiration Apnoea Hypopnoea Index (AHI) (Median events/hour, IQR) 34.5 (19 - 77) 29.4 (15 - 57) Treatment recommendation (%, 95% CI) CPAP 69 (59 - 78) 67 (56 - 76) ENT referral 3 (1 - 9) 7 (0 - 6) Lifestyle modification 42 (32 - 52) 14 (8 - 23)* Bilevel ventilation 1 (0 - 6) Follow-up for 12 months following diagnostic study Failed to attend any reviews (%, 95% CI) 38 (27 - 49) 19 (11 - 30)* Time to first review following diagnostic study (Median weeks, IQR) 22.3 (9.9 - 33.3) 20.6 (12.4 - 32.1) Machines can be ‘fragile’ *p<0.05 www.bakeridi.edu.au www.jcu.edu.au cindy.woods@jcu.edu.au