Prevalence of Depression amongst HIV Infected Adolescents in Malawi

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Presentation transcript:

Prevalence of Depression amongst HIV Infected Adolescents in Malawi M.H. Kim, A.C. Mazenga, A. Devendra, S. Ahmed. C. Sharp, J.K. Mhango, M. Bvumbwe, M. Machika, W. Kamiyango, A. Munthali, P.N. Kazembe xxx00.#####.ppt 11/9/2018 12:50:18 PM

Background and Study Aims As countries scale up pediatric services in Southern Africa, the number of Adolescents Living with HIV (ALHA) is rising Depression in HIV-infected persons is the most commonly occurring psychiatric disorder and is associated with poor treatment outcomes (HIV Clinical Resource, 2010, AVERT, 2011 Do et al, 2010; Gonzalez et al, 2011; Holzemer et al, 1999 & Reda & Biadgiligin, 2012, Carrico et al, 2011; Holzemer et al 1999 Scarcity of data regarding depression in youth in Malawi hinders the development of appropriate interventions. Study Aim: To estimate the prevalence of depression amongst adolescents aged 12 to 18 years old vertically infected with HIV in Malawi xxx00.#####.ppt 11/9/2018

Methods Study Design: quantitative cross-sectional study Study population: convenience sample of adolescents 12 – 18 years vertically infected with HIV presenting to care at the Baylor Clinic (Central Malawi), and Zomba Central Hospital ART clinic (Southern Malawi) Data collection: Depression Screening Tools Beck’s Depression Inventory (BDI) – II (Beck et al, 2006). Children’s Depression Inventory (CDI) II-Short (Kovacs, 2004). *Gold Standard: Children’s Depression Rating Scale-revised (CDRS-r) Socio-demographic, Behavioral & Adherence Questionnaire (SDBAQ) Medical Data Extraction Form (MDEF)

Results Recruited 562; 56% (315) female; 44% (247) male Mean age was 14.5 yrs Suicidal symptoms expressed in 7.2% (40) of the participants 1.1% (6) actively suicidal at the time of interview

Results Prevalence of Depression by Screening Tool Depression Screening Tool Total %(n), N=562 Female %(n), N=315 Male %(n), N=247 P-value BDI-II (cut-off = 17) 25.6%(144) 28.9%(91) 21.5%(53) <0.05 CDI-2 short (cut-off = 65) 20.8%(117) 19.7%(62) 22.3%(55) =0.45 CDRS – R Clinical assessment (cut-off = 55) 18.9%(106) 21.6(68) 15.4%(38) =0.06 - Make sure tables are same format/color xxx00.#####.ppt 11/9/2018

Closing Remarks High prevalence of depression amongst Malawian adolescents vertically infected with HIV in this setting, highlights the need for screening and availability of treatment services for adolescents living with HIV & AIDS Convenience sample of adolescents at two metropolitan clinics, not necessarily representative of adolescents throughout Malawi Currently analyzing the psychometric properties of the screening tools for use in ALHA in Malawi Research on factors associated with depression in ALHA is needed

Many thanks to Study participants/caregivers Research Team Texas Children’s Hospital Global Health program The Executive Director BCM-CFM, Dr P. Kazembe The Hospital Director ZCH, Dr Joshua The Medical Program Manager and staff, Dignitas International – Zomba Center for AIDS research (CFAR), Houston, USA COE Clinicians/doctors/nurses/social workers/psychotherapist Teen Club Teams from Zomba Central Hospital ART Clinic and Baylor Clinical Centre of Excellence All Baylor Malawi staff and Zomba Central ART Clinic staff.

Thank you for your Attention!