Physical health conditions and quality of life in adults with primary immunodeficiency diagnosed during childhood: A French Reference Center for PIDs.

Slides:

Advertisements

Similar presentations

Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing Danielle C.M. Belgrave, MSc,

Advertisements

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,

Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.

Endoplasmic reticulum stress influences bronchial asthma pathogenesis by modulating nuclear factor κB activation So Ri Kim, MD, PhD, Dong Im Kim, MS, Mi.

Morbidity and mortality from ataxia-telangiectasia are associated with ATM genotype Romain Micol, MD, MPH, PhD, Lilia Ben Slama, PhD, Felipe Suarez, MD,

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

Risk of an asthma exacerbation after bariatric surgery in adults

Clarification concerning amoxicillin skin testing

Treatment of hypogammaglobulinemia in adults: A scoring system to guide decisions on immunoglobulin replacement Shradha Agarwal, MD, Charlotte Cunningham-Rundles,

Quoting a landmark paper on the beneficial effects of probiotics

Autoimmune and inflammatory manifestations occur frequently in patients with primary immunodeficiencies Alain Fischer, MD, PhD, Johan Provot, MSc, Jean-Philippe.

Successful allogeneic hematopoietic stem cell transplantation for DOCK8 deficiency Vincent Barlogis, MD, Claire Galambrun, MD, Hervé Chambost, MD, Sylvie.

Optimal dose, efficacy, and safety of once-daily sublingual immunotherapy with a 5– grass pollen tablet for seasonal allergic rhinitis Alain Didier, MD,

Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD

Treatment of hypogammaglobulinemia in adults: A scoring system to guide decisions on immunoglobulin replacement Shradha Agarwal, MD, Charlotte Cunningham-Rundles,

Incident asthma and Mycoplasma pneumoniae: A nationwide cohort study

Is 9 more than 2 also in allergic airway inflammation?

Desensitization to Chemotherapeutic Agents

Joe K. Gerald, MD, PhD, Roni Grad, MD, William C. Bailey, MD, Lynn B

Hospitalization rates and prognosis of patients with anaphylactic shock in Denmark from 1995 through 2012 Anni Nørgaard Jeppesen, MD, Christian Fynbo.

Rising prevalence of asthma is sex-specific in a US farming population

Morbidity and mortality from ataxia-telangiectasia are associated with ATM genotype Romain Micol, MD, MPH, PhD, Lilia Ben Slama, PhD, Felipe Suarez, MD,

Occurrence of myelodysplastic syndrome in 2 patients with reticular dysgenesis Chantal Lagresle-Peyrou, PhD, Bénédicte Neven, MD, Emmanuelle Six, PhD,

Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J

Katherine A. Vierk, MPH, Kathleen M. Koehler, PhD, MPH, Sara B

Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis George Philip, MD, Janet van Adelsberg, MD, Thomas Loeys, PhD, Nancy.

Physician needs in health informatics: Just ask the docs

Peter M. Wolfgram, MD, David B. Allen, MD

William J. Calhoun, MD, Tmirah Haselkorn, PhD, Dave P

Jewlya Lynn, PhD, Sophie Oppenheimer, MS, MPH, Lorena Zimmer, MA

Debra J. Palmer, PhD, Thomas R. Sullivan, BMa&CompSc(Hons), Michael S

Roles of arginase variants, atopy, and ozone in childhood asthma

Genetic diagnosis of primary immunodeficiencies: A survey of the French national registry Nizar Mahlaoui, MD, PhD, Capucine Picard, MD, PhD, Perrine.

Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation Leif Bjermer, MD Journal of Allergy.

Food allergy in patients with primary immunodeficiency diseases: Prevalence within the US Immunodeficiency Network (USIDNET) Karen S. Tuano, MD, Jordan.

Tolerated wasp sting challenge improves health-related quality of life in patients allergic to wasp venom Jörg Fischer, MD, Martin Teufel, MD, Alexandra.

Atopic dermatitis: A practice parameter update 2012

Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management Scott H. Sicherer, MD, Hugh A. Sampson, MD Journal.

Biosimilars and drug development in allergic and immunologic diseases

Daphne Koinis-Mitchell, PhD, Timothy Craig, DO, Cynthia A

A cluster-randomized trial shows telephone peer coaching for parents reduces children's asthma morbidity Jane M. Garbutt, MB, ChB, Yan Yan, MD, PhD,

Peter Vadas, MD, PhD, Boris Perelman, PhD, Gary Liss, MD, MS

William T. Shearer, MD, PhD, Alain Fischer, MD, PhD

What is an “eosinophilic phenotype” of asthma?

Autophagy: Nobel Prize 2016 and allergy and asthma research

News & Notes Journal of Allergy and Clinical Immunology

Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment

Advances in the approach to the patient with food allergy

Geographic variability in childhood asthma prevalence in Chicago

Protective effect of IgM against colonization of the respiratory tract by nontypeable Haemophilus influenzae in patients with hypogammaglobulinemia Romain.

Asthma control can be maintained when fluticasone propionate/salmeterol in a single inhaler is stepped down Eric D. Bateman, MD, Loretta Jacques, PhD,

CD45RA depletion in HLA-mismatched allogeneic hematopoietic stem cell transplantation for primary combined immunodeficiency: A preliminary study Fabien.

News Beyond Our Pages Journal of Allergy and Clinical Immunology

Anaphylaxis during anesthesia in France: An 8-year national survey

Risk of oral food challenges

Machine learning, natural language programming, and electronic health records: The next step in the artificial intelligence journey? Neil Mehta, MBBS,

Change in visual analog scale score in a pragmatic randomized cluster trial of allergic rhinitis Philippe-Jean Bousquet, MD, Christophe Combescure, PhD,

Acid-suppressive drug use in pregnancy and the toddler's asthma risk: A crossover, case-control study Bianca Mulder, BSc, Catharina Carolina Maria Schuiling-Veninga,

Thunderstorm-related asthma attacks

Measles and immunomodulation

Guus A. Westerhof, MD, Elise M. Vollema, MD, Els J

Päivi M. Salo, PhD, Samuel J. Arbes, DDS, MPH, PhD, Patrick W

Macrolide antibiotics and asthma treatment

Asthma: The past, future, environment, and costs

Environmental factors and eosinophilic esophagitis

Efficacy and safety of thalidomide in patients with inflammatory manifestations of chronic granulomatous disease: A retrospective case series Nicolas.

Confirmation and improvement of criteria for clinical phenotyping in common variable immunodeficiency disorders in replicate cohorts Helen Chapel, MA,

Asthma, COPD, and overlap in a national cohort: ACO on a gradient

Natural history of cow’s milk allergy

Primary prevention of asthma and allergy

Presentation transcript:

Physical health conditions and quality of life in adults with primary immunodeficiency diagnosed during childhood: A French Reference Center for PIDs (CEREDIH) study Vincent Barlogis, MD, Nizar Mahlaoui, MD, Pascal Auquier, MD, PhD, Isabelle Pellier, MD, PhD, Fanny Fouyssac, MD, Camille Vercasson, MS, Maya Allouche, SC, Carolina Brito De Azevedo, SC, Felipe Suarez, MD, PhD, Despina Moshous, MD, PhD, Bénédicte Neven, MD, PhD, Marlène Pasquet, MD, PhD, Eric Jeziorski, MD, PhD, Nathalie Aladjidi, MD, Nicolas Schleinitz, MD, PhD, Caroline Thomas, MD, Virginie Gandemer, MD, PhD, Françoise Mazingue, MD, Patrick Lutz, MD, Olivier Hermine, MD, PhD, Capucine Picard, MD, PhD, Stéphane Blanche, MD, PhD, Gérard Michel, MD, Alain Fischer, MD, PhD Journal of Allergy and Clinical Immunology Volume 139, Issue 4, Pages 1275-1281.e7 (April 2017) DOI: 10.1016/j.jaci.2016.08.027 Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Distribution of health condition categories. Percentage of adults with grade 4 or grade 3-4 health conditions according to health condition categories. Journal of Allergy and Clinical Immunology 2017 139, 1275-1281.e7DOI: (10.1016/j.jaci.2016.08.027) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Quality of life of patients with grade 4 health conditions. *P < .01 and **P < .001. Journal of Allergy and Clinical Immunology 2017 139, 1275-1281.e7DOI: (10.1016/j.jaci.2016.08.027) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Quality of life of patients with grade 3 or 4 health conditions. *P < .01 and **P < .001. Journal of Allergy and Clinical Immunology 2017 139, 1275-1281.e7DOI: (10.1016/j.jaci.2016.08.027) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Flow chart: status of patients registered in the F-CILC (June 2015). Journal of Allergy and Clinical Immunology 2017 139, 1275-1281.e7DOI: (10.1016/j.jaci.2016.08.027) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Burden of health conditions reported by adults with PIDs diagnosed during childhood. Percentages of adults with grade 4 or grade 3 to 4 health conditions are shown. Journal of Allergy and Clinical Immunology 2017 139, 1275-1281.e7DOI: (10.1016/j.jaci.2016.08.027) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions