The complex world of kidney microRNAs

Slides:

Advertisements

Similar presentations

From: Emerging Roles for MicroRNAs in Perioperative Medicine

Advertisements

Volume 80, Issue 4, Pages (August 2011)

New Hope for a MicroRNA Therapy for Liver Cancer

C. Belair, F. Darfeuille, C. Staedel

The Case ∣ Acute renal failure and anemia

Driving change: kidney proximal tubule CSF-1 polarizes macrophages

Rafael Kramann, Marcus J. Moeller Kidney International

Volume 80, Issue 10, Pages (November 2011)

Molecular mechanisms of diabetic renal hypertrophy

TGF-β isoforms in renal fibrogenesis

EGFR signaling in renal fibrosis

MicroRNAs in the Pathogenesis of Lung Cancer

Volume 84, Issue 6, Pages (December 2013)

JAK/STAT signaling in renal diseases

Better nephrology for mice—and man

Volume 71, Issue 8, Pages (April 2007)

Volume 84, Issue 2, Pages (August 2013)

Volume 84, Issue 2, Pages (August 2013)

Bioavailable vitamin D in chronic kidney disease

Volume 133, Issue 1, Pages (April 2008)

Comorbidity and confounding in end-stage renal disease

Volume 74, Issue 3, Pages (August 2008)

Volume 73, Issue 4, Pages (February 2008)

Severe exfoliative skin rash with icodextrin

Volume 86, Issue 2, Pages (August 2014)

The role of protein kinase C activation in diabetic nephropathy

Volume 75, Issue 8, Pages (April 2009)

Weei-Yuarn Huang, Seymour Rosen Kidney International

Claudine S. Bonder, Lisa M. Ebert Kidney International

Saulo Klahr, Jeremiah J. Morrissey Kidney International

Kenar D. Jhaveri, Steven Fishbane Kidney International

Osteopontin in diabetic nephropathy: signpost or road?

Modulating kidney transplant interstitial fibrosis and tubular atrophy: is the RAAS an important target? Hatem Amer, Matthew D. Griffin Kidney International

Molecular Therapy - Nucleic Acids

Driving change: kidney proximal tubule CSF-1 polarizes macrophages

It takes two to Twist Kidney International

Adenosine A2A agonists as therapy for glomerulonephritis

Volume 69, Issue 12, Pages (June 2006)

Volume 69, Issue 3, Pages (February 2006)

Volume 85, Issue 5, Pages (May 2014)

Volume 74, Issue 8, Pages (October 2008)

Volume 87, Issue 3, Pages (March 2015)

Old friends form alliance against podocytes

CD4+ T cells: a potential player in renal fibrosis

Nephrology Crossword: Glomerulonephritis

Mechanisms of tubulointerstitial injury in IgA nephropathy

Insulin resistance and hypertension: new insights

Volume 76, Issue 1, Pages 6-7 (July 2009)

It's not over till the last glomerulus forms

Volume 82, Issue 9, Pages (November 2012)

Volume 69, Issue 11, Pages (June 2006)

Guang-Huar Young, Vin-Cent Wu Kidney International

Stephen O'Neill, Jeremy Hughes Kidney International

Markus Bitzer, Iddo Z. Ben-Dov, Thomas Thum Kidney International

Engineering parathyroid cells to treat secondary hyperparathyroidism

Nuclear factors, hs1,2 enhancer and IgA nephropathy

Molecular mechanisms of renal hypertrophy: Role of p27Kip1

Volume 80, Issue 10, Pages (November 2011)

Volume 83, Issue 4, Pages (April 2013)

Hydrogen sulfide to the rescue in obstructive kidney injury

Volume 72, Issue 11, Pages (December 2007)

David A. Ferenbach, David C. Kluth, Jeremy Hughes Kidney International

Volume 70, Issue 3, Pages (August 2006)

Volume 71, Issue 9, Pages (May 2007)

Kathryn J. Wiggins, Darren J. Kelly Kidney International

Dana V. Rizk, David G. Warnock Kidney International

Volume 75, Issue 6, Pages (March 2009)

Volume 75, Issue 8, Pages (April 2009)

Laura M. Krinsky, William J. Levine Kidney International

Renoprotection with vitamin D: Specific for diabetic nephropathy?

Presentation transcript:

The complex world of kidney microRNAs Balakuntalam S. Kasinath, Denis Feliers Kidney International Volume 80, Issue 4, Pages 334-337 (August 2011) DOI: 10.1038/ki.2011.165 Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 1 A schematic showing the generation and actions of miRNA. Ago, Argonaute; DGCR8, DiGeorge syndrome critical region 8; eIF4E, eukaryotic initiation factor 4E; GW182, glycine-tryptophan protein-182; nt, nucleotides; RISC, miRNA-induced silencing complex; TARBP, transactivation-responsive RNA-binding protein. Kidney International 2011 80, 334-337DOI: (10.1038/ki.2011.165) Copyright © 2011 International Society of Nephrology Terms and Conditions

Figure 2 Role of miRNA in diabetic nephropathy. miR, miRNA; PTEC, proximal tubule epithelial cells; T1D, type 1 diabetes; T2D, type 2 diabetes; TGF-β1, transforming growth factor-β1. Arrows indicate stimulation; bars indicate inhibition. Kidney International 2011 80, 334-337DOI: (10.1038/ki.2011.165) Copyright © 2011 International Society of Nephrology Terms and Conditions