Harvey B. Simon, MD The American Journal of Medicine

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Presentation transcript:

Exercise and Health: Dose and Response, Considering Both Ends of the Curve Harvey B. Simon, MD The American Journal of Medicine Volume 128, Issue 11, Pages 1171-1177 (November 2015) DOI: 10.1016/j.amjmed.2015.05.012 Copyright © 2015 Elsevier Inc. Terms and Conditions

Figure The risk of heart attack as a function of weekly exercise in 16,936 male alumni of Harvard College. As compared with sedentary men, those who expended 2000-3000 kcal/week in exercise enjoyed a 36% lower risk of myocardial infarction. Higher levels of total exercise did not confer additional protection, but strenuous sports enhanced the effect of total energy expenditure to a modest degree. Source: Paffenbarger RS, Wing AL, Hyde RT. Physical activity as an index of heart attack risk in college alumni. Am J Epidemiol. 1978;108:161-175 (p 166).5 The American Journal of Medicine 2015 128, 1171-1177DOI: (10.1016/j.amjmed.2015.05.012) Copyright © 2015 Elsevier Inc. Terms and Conditions