Concept 4: Analyzing Cell Communication

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Presentation transcript:

Concept 4: Analyzing Cell Communication Chapter 11 Pg. 57-60 in Holtzclaw

Cell Communication You must know: The three stages of cell communication: reception, transduction, and response (the signal transduction pathway!) Applications/Examples!

Signal Transduction Pathway Reception Transduction Response

Signal Transduction Pathway Reception: Receptors undergo changes in shape due to an environmental stimulus

Signal Transduction Pathway Transduction: Amplification of signal through a multistep pathway Allows small signal to produce large cellular response Uses protein kinases (phosphorylation cascade) and second messengers (Ca2+ and cAMP)

Signal Transduction Pathway Response: Two ways response is accomplished: Transcriptional Modification: ↑ or ↓ mRNA production (turning genes on/off) Post-Translational Modification: Activates existing enzyme molecules

Signal Transduction Reception Transduction Response Act Out!

Sample Questions Describe the signal transduction pathway in terms of reception, transduction, and response. Explain the two ways that responses can be accomplished A hormone molecule ends up blocking RNA polymerase from attaching to a specific gene. Is this response transcriptional modification or post-translational?