Figure 1 Male infertility and assisted reproduction globally

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Figure 1 Male infertility and assisted reproduction globally Figure 1 | Male infertility and assisted reproduction globally. a | Map of the prevalence of male factor infertility in the world. The prevalence of male infertility was calculated as the product of prevalence of infertility and the percentage of male factor infertility (Supplementary information S1 (table)). b | Trends in sperm concentration and motility, and overall male and female factor infertility rates in the USA between 2003 and 2013 (Ref. 238). The increase in the infertility curves between 2010 and 2011 are in part attributed to the updated reference limits for semen quality from the WHO. c | Total fertility rate between 1995 and 2014 for different regions and globally. The dashed line represents the fertility rate required to preserve the current world population239. d | Increasing number of assisted reproductive technology (ART) cycles and plateaued success rate of ART per cycle (quantified as a percentage of live-birth delivered per cycle) in the world between 2000 and 2010 (Supplementary information S2 (table)). Nosrati, R. et al. (2017) Microfluidics for sperm analysis and selection Nat. Rev. Urol. doi:10.1038/nrurol.2017.175