A Practical Guide to the Prevention of Surgical Adhesions

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Presentation transcript:

A Practical Guide to the Prevention of Surgical Adhesions

Fibrinolytic System Inhibitors vs Activators

Pathogenesis of Adhesions

Etiology of Adhesion Formation

Prevalence of Adhesions Following Surgical Procedures

Adhesion Incidence Following C-Section Most Common Surgery in the World

Prevalence of Adhesions Following Laparoscopic Procedures

Predicting Adhesion Formation

Burden of Adhesions

Sequelae of Adhesions

Adhesion Prevention Strategies

Adhesion Prevention Strategies Pharmacologic Interventions

Adhesion Prevention Solutions/Gels

P.O.P.A. Study Icodextrin 4% Solution

Adhesion Prevention Barrier Devices

Oxidized Regenerated Cellulose

Oxidized Regenerated Cellulose 10-study Meta-analysis

Oxidized Regenerated Cellulose Usage Caveats

HA/CMC Abdominal Study

HA/CMC Safety in Abdominal Surgery

HA/CMC Myomectomy Study Percentage of Patients with No Adhesions

HA/CMC Limitations

Barrier Agents’ Efficacy Review of 18 Randomized Controlled Trials

Future Directions

Summary

Abbreviations

References

References (cont)

References (cont)

References (cont)

References (cont)

References (cont)