Statistical Considerations for Immunohistochemistry Panel Development after Gene Expression Profiling of Human Cancers Rebecca A. Betensky, Catherine.

Slides:

Advertisements

Similar presentations

Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease- Causing Point Mutations Renee P. Stokowski, David R. Cox The American.

Advertisements

Gene Preference in Maple Syrup Urine Disease Mary M. Nellis, Dean J. Danner The American Journal of Human Genetics Volume 68, Issue 1, Pages (January.

SORVEGLIANZA DELLE MALATTIE NEOPLASTICHE. Cancer statistics, 2013 CA: A Cancer Journal for Clinicians Volume 63, Issue 1, pages 11-30, 17 JAN 2013 DOI:

Measurement of Relative Copy Number of CDKN2A/ARF and CDKN2B in Bladder Cancer by Real-Time Quantitative PCR and Multiplex Ligation-Dependent Probe Amplification.

Nine Novel Germline Gene Variants in the RET Proto-Oncogene Identified in Twelve Unrelated Cases Syed A. Ahmed, Karen Snow-Bailey, W. Edward Highsmith,

A Multiplex qPCR Gene Dosage Assay for Rapid Genotyping and Large-Scale Population Screening for Deletional α-Thalassemia Wanjun Zhou, Ge Wang, Xuefeng.

Development of a Novel One-Tube Isothermal Reverse Transcription Thermophilic Helicase-Dependent Amplification Platform for Rapid RNA Detection James Goldmeyer,

Telomerase Activity and Expression of Telomerase RNA Component and Telomerase Catalytic Subunit Gene in Cervical Cancer Kenji Nakano, Elizabeth Watney,

CyclinD1/CyclinD3 Ratio by Real-Time PCR Improves Specificity for the Diagnosis of Mantle Cell Lymphoma Carol D. Jones, Katherine H. Darnell, Roger A.

Quantification of Parvovirus B19 DNA Using COBAS AmpliPrep Automated Sample Preparation and LightCycler Real-Time PCR Stefan Schorling, Gunnar Schalasta,

Design and Multiseries Validation of a Web-Based Gene Expression Assay for Predicting Breast Cancer Recurrence and Patient Survival Ryan K. Van Laar The.

Accurate Molecular Characterization of Formalin-Fixed, Paraffin-Embedded Tissues by microRNA Expression Profiling Anna E. Szafranska, Timothy S. Davison,

Enterococcus faecalis Induces Inflammatory Bowel Disease in Interleukin-10 Knockout Mice Edward Balish, Thomas Warner The American Journal of Pathology.

Vida Kocbek, Katja Vouk, Nick A. Bersinger, Michael D

Hybrid Model Integrating Immunohistochemistry and Expression Profiling for the Classification of Carcinomas of Unknown Primary Site Barbara A. Centeno,

Toward Universal Flavivirus Identification by Mass Cataloging

Real-Time PCR for Chlamydia pneumoniae Utilizing the Roche Lightcycler and a 16S rRNA Gene Target Justin Hardick, Nancy Maldeis, Mellisa Theodore, Billie.

Laboratory Guidelines for Detection, Interpretation, and Reporting of Maternal Cell Contamination in Prenatal Analyses Narasimhan Nagan, Nicole E. Faulkner,

Eligibility Criteria and Genetic Testing Results from a High-Risk Cohort for Hereditary Breast and Ovarian Cancer Syndrome in Southeastern Ontario Ricardo.

Identification and Characterization of Optimal Gene Expression Markers for Detection of Breast Cancer Metastasis John Backus, Todd Laughlin, Yixin Wang,

Kirby Siemering, Shehnaaz S. M. Manji, Wendy M

Molecular Genetics of Pediatric Soft Tissue Tumors

Development and Validation of a Preanalytic Procedure for Performing the cobas HPV Test in SurePath Preservative Fluid Mark D. Krevolin, David Hardy,

Mutation Screening in Juvenile Polyposis Syndrome

162. Stability of Polymer/Plasmid DNA Complexes In Vitro and In Vivo

Increased Sensitivity of the Roche COBAS AMPLICOR HCV Test, Version 2

Maxim B. Freidin, Neesa Bhudia, Eric Lim, Andrew G

Design and Multiseries Validation of a Web-Based Gene Expression Assay for Predicting Breast Cancer Recurrence and Patient Survival Ryan K. Van Laar

Microarray Technique, Analysis, and Applications in Dermatology

Rapid Real-Time PCR Assays for Detection of Klebsiella pneumoniae with the rmpA or magA Genes Associated with the Hypermucoviscosity Phenotype Laurie.

The History and Impact of Molecular Coding Changes on Coverage and Reimbursement of Molecular Diagnostic Tests Susan J. Hsiao, Mahesh M. Mansukhani,

Patrick R. Murray The Journal of Molecular Diagnostics

Chronic Myeloid Leukemia

William L. Gerald, M.D., Ph.D, 1954–2008

Kyong-Ah Yoon, Sohee Park, Sang Hee Lee, Jin Hee Kim, Jin Soo Lee

SeqSharp The Journal of Molecular Diagnostics

BRAF Mutation Testing in Solid Tumors

Duplex Ratio Tests as Diagnostic Biomarkers in Malignant Melanoma

Reliable Transcript Quantification by Real-Time Reverse Transcriptase-Polymerase Chain Reaction in Primary Neuroblastoma Using Normalization to Averaged.

The Molecular Pathology of Primary Immunodeficiencies

Report of New Haplotype for ABCC2 Gene

Vida Kocbek, Katja Vouk, Nick A. Bersinger, Michael D

Robert S. Stern Journal of Investigative Dermatology

Suzanne D. Vernon, Elizabeth R. Unger, Mangalathu Rajeevan, Irina M

Molecular Therapy Volume 7, Issue 5, (May 2003) DOI: /S (16)

Ayalew Tefferi, Pierre Noel, Curtis A. Hanson

Avoiding Pitfalls in Molecular Genetic Testing

847. Eradication of Therapy-Resistant Human Prostate Tumors Using an Ultrasound Guided Site-Specific Cancer Terminator Virus Delivery Approach Molecular.

Mutations in the Kinase Domain of the HER2/ERBB2 Gene Identified in a Wide Variety of Human Cancers Wenhsiang Wen, Wangjuh (Sting) Chen, Nick Xiao, Ryan.

Designer Lipids Advance Systemic siRNA Delivery

Erratum The American Journal of Human Genetics

Gayatry Mohapatra, Rebecca A. Betensky, Ezra R

Inherited Cardiomyopathies

674. Molecular, Biochemical and Biomechanical Analysis of Articular Cartilage Repaired with Genetically Modified Chondrocytes Expressing Insulin-Like.

Society for Investigative Dermatology 2010 Meeting Minutes

Molecular Therapy Volume 18, Pages S260-S261 (May 2010) DOI: /S (16)

Statistical Treatment of Fluorescence in Situ Hybridization Validation Data to Generate Normal Reference Ranges Using Excel Functions Allison L. Ciolino,

Use of Pyrosequencing of 16S rRNA Fragments to Differentiate between Bacteria Responsible for Neonatal Sepsis Jeanne A. Jordan, Allyson R. Butchko, Mary.

Karen Snow-Bailey, Ph.D., 1961–2006

Custom Design of a GeXP Multiplexed Assay Used to Assess Expression Profiles of Inflammatory Gene Targets in Normal Colon, Polyp, and Tumor Tissue Janice.

Jie Hu, Malini Sathanoori, Sally J. Kochmar, Urvashi Surti

Journal of Investigative Dermatology

740. Prevention of Radiation-Induced Lung Injury by Administration of Gene-Modified Mesenchymal Stem Cells Molecular Therapy Volume 20, Pages S285-S286.

Xiangfeng Cui, Helen Feiner, Honghua Li

Molecular Therapy Volume 21, Pages S247-S248 (May 2013)

86. A Highly Compact Epitope-Based Marker Suicide Gene for Safer and Easier Adoptive T-Cell Gene Therapy Molecular Therapy Volume 20, Pages S35-S36.

Angiotensin I-Converting Enzyme

Monique A. Johnson, Marvin J. Yoshitomi, C. Sue Richards

CAT25 Is a Mononucleotide Marker to Identify HNPCC Patients

The History and Impact of Molecular Coding Changes on Coverage and Reimbursement of Molecular Diagnostic Tests Susan J. Hsiao, Mahesh M. Mansukhani,

Presentation transcript:

Statistical Considerations for Immunohistochemistry Panel Development after Gene Expression Profiling of Human Cancers Rebecca A. Betensky, Catherine L. Nutt, Tracy T. Batchelor, David N. Louis The Journal of Molecular Diagnostics Volume 7, Issue 2, Pages 276-282 (May 2005) DOI: 10.1016/S1525-1578(10)60555-7 Copyright © 2005 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions

Figure 1 Schematic of study design using original Nutt et al data and new MGH data. Locations in the design where the assumptions are invoked are indicated. The Journal of Molecular Diagnostics 2005 7, 276-282DOI: (10.1016/S1525-1578(10)60555-7) Copyright © 2005 American Society for Investigative Pathology and Association for Molecular Pathology Terms and Conditions