Rapid Diagnostics and Stewardship: Combating the Rise of Antimicrobial Resistance

Overprescribing of Antibiotics in the United States

Antibiotic Resistance: A Growing Threat

Implications of Overprescribing

Overprescribing: Finding a Cure

ASP Objective: Patient Safety

Antimicrobial Stewardship Across the Continuum of Care

Linking Diagnostics to Stewardship: The Right Test for the Right Patient at the Right Time

RDTs Support Antimicrobial Stewardship

Path of Conventional Microbiology

RDTs: Biomarkers of Infection/Inflammation

Molecular RDTs: Culture Dependent

Molecular RDTs: Culture Independent

Case: 54-year-old Woman

Case: Test Results

Time to Determine Optimal Antibiotic Therapy: Traditional vs Rapid Diagnostic Methods

Beta Lactams More Effective Than Vancomycin Against MSSA

Faster Time to Effective Therapy Makes a Difference

Lower Overall Cost Per Episode Justified Higher Cost of RDT

Use of MALDI-TOF Decreased Time to Effective Therapy by 41 Hours

Implementation of RDTs: Short-Term Considerations

Implementation of RDTs: Short-Term Considerations (cont)

Implementation of RDTs: Long-Term Considerations

Implementing RDTs: Keys to Success

Implementing RDTs: Keys to Success (cont)

ASPs: Nurses Are Critical

ASPs: The Role of Pharmacists

Concluding Remarks

Abbreviations

Abbreviations (cont)

Abbreviations (cont)