Figure 1 Role of innate lymphoid cells (ILCs) in steady state,

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Innate lymphoid cells in allergic and nonallergic inflammation

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Figure 1 Role of innate lymphoid cells (ILCs) in steady state, non-autoimmune and autoimmune chronic inflammatory diseases Figure 1 | Role of innate lymphoid cells (ILCs) in steady state, non-autoimmune and autoimmune chronic inflammatory diseases. ILCs can exhibit multiple antimicrobial effector functions at barrier surfaces, protecting against infectious agents including helminths, viruses, intracellular parasite and protozoa, extracellular bacteria and fungi. ILCs are divided into three groups; functional plasticity is exhibited between these ILC subsets, depending on the inflammatory milieu. ILCs are dysregulated in a variety of non-autoimmune and autoimmune chronic inflammatory diseases that affect barrier functions, suggesting that they contribute to pathology. ANCA, antineutrophil cytoplasmic autoantibody. Shikhagaie, M. M. et al. (2017) Innate lymphoid cells in autoimmunity: emerging regulators in rheumatic diseases Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2016.218