Ant Uveitis Uveitis Posterior Uveitis Pan Uveitis Iritis iridocyclitis

Viral Uveitis

Human viruses D.N.A Viruses R.N.A Viruses Simple viruses Complex viruses

Viral Infection Direct Contact Ingestion Inhalation

Infection Begins On An Epithelial Or Mucosal Surface And Spreads To Deeper Tissues And May Spread Through The Body Via The Blood Stream Lamphatics Or Neural Circuits.

Herpes Viridae Family HSV , VZV , CMV And EBV

Herpes Simplex Virus Varicella – Zoster Virus

Anterior Uveitis Acute Anterior Uveitis Is Often Associated With Herpetic Viral Disease Usually With Keratoiritis Secondary To Corneal Disease

In Many Cases The Inflammation Becomes Chronic.

Nearby 100% Of Those Older Than 60 Years Of Age Harbor HSV In Their Trigeminal Ganglia At Autopsy.

One Theird Of The World Population Suffers From Recurrent Infection.

Therefore HSV Infections Represent A Large And Worldwide Public Health Problem

HSV HSV Type 1 : Infects Above The Waist HSV Type 2 : Infects Below The Waist (Genital Infection)

HSV Primary Infection Skin Mucosal Surfaces Via Nerve Axons To Trigemial ganglion

Reactivation In The Absence Of Recognized Primary Infection In Any Of The 3 Branches Approximately 15% Of US Population Has A History Of External Ocular HSV Infection And One Fifth Develop Stromal Keratitis, The Most Common Blinding Manifestation Of Infection.

Primary Ocular Infection

Unilateral Blepharo Conjunctivities Follicular Preauricular Lymph Node Vesicles On The Skin May Have Epithelial Keratitis

Stromal Keratitis And Uveitis Are Uncommon In Primary Infection

Anterior Uveitis Is Often With Herpetic Viral Disease In A Reactivation Of HSV Infection Keratouveitis Iritis Trabeculitis Iridocyclitis

Bilateral Anterior Uveitis In Only 3% Of Cases Probably Immuncompromised.

Varicella – Zoster Virus (VZV) As HSV May Induce Keratitis Keratoiritis Iridocyclitis Bilateral Mild Self Limited

Cutaneous Vesicles At The Side Of The Tip Of The Nose (Hutchinson Sign) Indicate Nasocilliary Nerve Involvement And The Eye Will Be Affected.

Clinical Manifestations

Perilimbal Injection Myosis Pain Anterior Chambar Reactions

Kerato Uveitis --Stromal --Endothelial Iritis Iridocyclitis

K P, S P S Pupillary Mambran

Iris Atrophy P S With Distortion Of The Pupil Hypopion

Trabeculitis Glaucoma -- Acut -- Chronic

Management

Topical Corticosteroids Cycloplegic Agents Topical Antiviral Agents Systemic Antivirals

Acyclovir Famciclovir Valacyclovir

Varicella – Zoster (VZV) As SHV May Case Keratoiritis In Differential Diagnosis Chromic Unilateral Iridocyclitis

VZV And Varicella (Chickenpox) Acute Mild Nongranulomatous Self-Limited Billateral Iridocyclitis Huchinson Sign (Nasociliary Nerve Involvement) Great Likelihood Of Eye Involvement

ضمن عرض پوزش بدلیل حجم بالای LECTUER ادامه اسلایدها امکان پذیر نمیباشد در صورت نیاز به ادامه لطفا به واحد سمعی و بصری مرکز آموزشی درمانی فیض مراجعه و یا با شماره تلفن 03114476010 داخلی 392 تماس حاصل نمائید با تشکر