Radiolabeled Anti-CD45 Antibody with Reduced-Intensity Conditioning and Allogeneic Transplantation for Younger Patients with Advanced Acute Myeloid Leukemia.

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Presentation transcript:

Radiolabeled Anti-CD45 Antibody with Reduced-Intensity Conditioning and Allogeneic Transplantation for Younger Patients with Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome Raya Mawad, Ted A. Gooley, Joseph G. Rajendran, Darrell R. Fisher, Ajay K. Gopal, Andrew T. Shields, Brenda M. Sandmaier, Mohamed L. Sorror, Hans Joachim Deeg, Rainer Storb, Damian J. Green, David G. Maloney, Frederick R. Appelbaum, Oliver W. Press, John M. Pagel Biology of Blood and Marrow Transplantation Volume 20, Issue 9, Pages 1363-1368 (September 2014) DOI: 10.1016/j.bbmt.2014.05.014 Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Estimated radiation absorbed doses per millicurie of 131I administered for all 15 patients. Biology of Blood and Marrow Transplantation 2014 20, 1363-1368DOI: (10.1016/j.bbmt.2014.05.014) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Estimates of the probability of OS, RFS, NRM, and relapse among all patients who received a therapeutic dose of 131I-BC8 Ab followed by TBI/FLU. Biology of Blood and Marrow Transplantation 2014 20, 1363-1368DOI: (10.1016/j.bbmt.2014.05.014) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions