Asthma Phenotypes Defined From Parameters Obtained During Recovery From a Hospital-Treated Exacerbation Rihuang Qiu, MD, Jiaxing Xie, MD, PhD, Kian Fan.

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Asthma Phenotypes Defined From Parameters Obtained During Recovery From a Hospital-Treated Exacerbation Rihuang Qiu, MD, Jiaxing Xie, MD, PhD, Kian Fan Chung, MD, PhD, Naijian Li, MD, Zhaowei Yang, PhD, Mengzhang He, MD, Jing Li, MD, Rongchang Chen, MD, Nanshan Zhong, MD, Qingling Zhang, MD, PhD The Journal of Allergy and Clinical Immunology: In Practice Volume 6, Issue 6, Pages 1960-1967 (November 2018) DOI: 10.1016/j.jaip.2018.02.012 Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 1 Flowchart describing the selection criteria of patients and the clinical data used for analysis. ATS, American Thoracic Society; COPD, chronic obstructive pulmonary disease; ERS, European Respiratory Society; GINA, Global Initiative for Asthma. The Journal of Allergy and Clinical Immunology: In Practice 2018 6, 1960-1967DOI: (10.1016/j.jaip.2018.02.012) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Figure 2 A, BMI; B, age; C, age of asthma onset; D, lung function: FEV1 (% predicted), FEV1/FVC (%), and FEF25-75 (% predicted); and E, sputum inflammatory cells: neutrophils (%) and eosinophils (%) between the 4 clusters as determined by cluster analysis. Data shown as mean ± SD (Fig 2, A-D) and median (interquartile range) (Fig 2, E). BMI, Body mass index. *P < .05; **P < .01. The Journal of Allergy and Clinical Immunology: In Practice 2018 6, 1960-1967DOI: (10.1016/j.jaip.2018.02.012) Copyright © 2018 American Academy of Allergy, Asthma & Immunology Terms and Conditions