Perspectives on Key MS Data From the Annual European MS Meeting

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Presentation transcript:

Perspectives on Key MS Data From the Annual European MS Meeting

Integrating MRI Cortical Lesions in the Diagnosis of MS

Integrating MRI Cortical Lesions in the Diagnosis of MS (cont)

CARE MS I & II: MRI-Detected Lesions and NEDA

CARE-MS I and II: Rate of BVL

Spinal Cord Volume

Brain Atrophy as a Surrogate Marker for MS Progression

Perspectives on Key MS Data From the Annual European MS Meeting

Long-Term Effect of Therapy Effect of Year of MS Diagnosis on Reaching EDSS of 6

CARE-MS II: 5-Year Outcomes in Patients With HAD at Baseline

CARE-MS I and II: Autoimmunity With Alemtuzumab

CARE-MS I and II: Autoimmunity With Alemtuzumab (cont)

Use of Modified MSFC to Assess Efficacy of Daclizumab HYP and IFN-β1a IM on 24-Week Sustained Disability Progression

Use of Modified MSFC to Assess Efficacy of Daclizumab HYP and IFN-β1a IM on 24-Week Sustained Disability Progression (cont)

ENDORSE: Study Design

ENDORSE: Results

Perspectives on Key MS Data From the Annual European MS Meeting

NEDA: Definitions

Prognosis: ADVANCE and ATTAIN*

Prognosis: FREEDOMS and FREEDOMS II

Prognosis: FREEDOMS and FREEDOMS II (cont)

Achieving NEDA: DECIDE

Achieving NEDA: CLARITY and ONWARD

NEDA as Long-Term Therapeutic Goal: CARE-MS

NEDA: Practice Implications

NEDA: Practice Implications (cont)

NEDA: Practice Implications (cont)

Perspectives on Key MS Data From the Annual European MS Meeting

EXPAND: Siponimod in SPMS

RADIANCE Extension -- Ozanimod: Design

RADIANCE Extension -- Ozanimod: Results

ORATORIO: Subgroup Analysis

Autologous HSCT

ASCEND: Subgroup Analysis -- Design

ASCEND: Subgroup Analysis – Results

Abbreviations

Abbreviations (cont)

Abbreviations (cont)