RESPIRATORY SYSTEM # 4 Gas exchange Gas transport Respiratory control 17 November 2008 RESPIRATORY SYSTEM # 4 Gas exchange Gas transport Respiratory control Lab this week: 3 Respiratory Case Studies on website. Bring calculator and textbook to lab Test # 3: Monday, 24 November

Only ¾ of riders exit at destination! Why? Figure 13.20 Gas Transport in blood like hormones: free (dissolved) and bound (to hemoglobin) Analogy of bus riders; Only ¾ of riders exit at destination! Why?

Landmark numbers to memorize. Table 13.07 Landmark numbers to memorize.

What happens in systemic capillaries? Figure 13.27 What happens in systemic capillaries? O2 bound to Hb does not contribute to partial pressure (no longer a dissolved gas!)

Table 13.08

Figure 13.26 Steep Flat

Figure 13.29 At 40 Torr, more DPG, higher temperature, and greater acidity (all indicative of increased metabolism) shift dissociation curve down (Hb has a lower affinity for O2) and thus more O2 is unloaded into the tissues.

Figure 13.34

Figure 13.28 Oxygen exchange

Carbon dioxide transport carbaminohemoglobin Chloride Shift CA = carbonic anhydrase Buffer Carbon dioxide transport

Figure 13.31 Hb can bind O2, CO2, and H+

Table 13.09

Cervical spinal cord injury Figure 13.32 Negative feedback loop for control of blood gases Cervical spinal cord injury

Figure 13.22

Name the components of the negative feedback loop Figure 13.40 Name the components of the negative feedback loop