Cancer Cachexia in GI Malignancies

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Presentation transcript:

Cancer Cachexia in GI Malignancies

Malnutrition is the most underappreciated complication of gastrointestinal malignancies

Malnutrition and weight loss are prevalent in cancer patients

Weight loss and overall survival in gastrointestinal malignancy

Weight loss and clinical outcomes in gastrointestinal malignancy

Nutritional support in GI malignancy: Do we practice in (un)conscious ignorance?

Cancer Cachexia: Definition

Sarcopenia: Definitions

Malnutrition: Impact of sarcopenia

Malnutrition: Impact of sarcopenia

Malnutrition and systemic inflammation

Frequency of side effects and probability of malnutrition

Treatment-related side effects negatively impact nutritional status

Malnutrition affects all aspects of gastrointestinal oncology management

Nutritional intervention can improve quality of life

Nutritional intervention can improve functional outcomes

Nutritional intervention can improve QOL and OS in advanced pancreatic cancer

Stabilization of weight improves overall survival in colorectal cancer

Early nutrition intervention has been shown to improve outcomes in cancer patients

Nutritional support for GI malignancies requires a multidisciplinary team approach

The question(s) thus remain for nutritional support in GI malignancy: How do we???

Providing nutritional support in GI malignancy: The TARGET approach

Nutrition Pathway: Role of dietitian

Malnutrition Screening Tool

PG-SGA-SF

PG-SGA-SF

MST vs PG-SGA

Full Nutrition Assessment

Determining Nutrition Intervention

Nutrition Care Plan

Nutrition Care Plan

Cachexia in GI Malignancies: Pharmacological agents

Cachexia in GI malignancies: Investigational agents

Managing cachexia in GI malignancy: How I do it