Practical management of acne for clinicians: An international consensus from the Global Alliance to Improve Outcomes in Acne  Diane M. Thiboutot, MD,

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Practical management of acne for clinicians: An international consensus from the Global Alliance to Improve Outcomes in Acne  Diane M. Thiboutot, MD, Brigitte Dréno, MD, PhD, Abdullah Abanmi, MD, Andrew F. Alexis, MD, MPH, Elena Araviiskaia, MD, PhD, Maria Isabel Barona Cabal, MD, Vincenzo Bettoli, MD, Flordeliz Casintahan, MD, Steven Chow, MD, Adilson da Costa, MD, MSc, PhD, Tam El Ouazzani, MD, Chee-Leok Goh, MD, Harald P.M. Gollnick, MD, Minerva Gomez, MD, Nobukazu Hayashi, MD, PhD, Maria Isabel Herane, MD, Juan Honeyman, MD, Sewon Kang, MD, Lajos Kemeny, MD, PhD, Raj Kubba, MD, Julien Lambert, MD, PhD, Alison M. Layton, MB ChB, James J. Leyden, MD, Jose Luis López-Estebaranz, MD, PhD, Nopadon Noppakun, MD, Falk Ochsendorf, MD, Cristina Oprica, MD, PhD, Beatriz Orozco, MD, Montserrat Perez, MD, Jaime Piquero-Martin, MD, MSc, Jo-Ann See, MD, Dae Hun Suh, MD, PhD, Jerry Tan, MD, Vicente Torres Lozada, MD, Patricia Troielli, MD, Leihong Flora Xiang, MD, PhD  Journal of the American Academy of Dermatology  Volume 78, Issue 2, Pages S1-S23.e1 (February 2018) DOI: 10.1016/j.jaad.2017.09.078 Copyright © 2017 Terms and Conditions

Fig 1 Illustration of differences in lesions of acne vulgaris that could affect overall assessment of acne severity but not lesion counts. Photos courtesy of DermQuest.com. Copyright © 2006 Galderma S.A. All rights reserved. Journal of the American Academy of Dermatology 2018 78, S1-S23.e1DOI: (10.1016/j.jaad.2017.09.078) Copyright © 2017 Terms and Conditions

Fig 2 Illustrative photos of severe inflammatory acne vulgaris, largely without nodules (A). B, Very severe acne with cysts. Photos courtesy of DermQuest.com. Copyright © 2006 Galderma S.A. All rights reserved. Journal of the American Academy of Dermatology 2018 78, S1-S23.e1DOI: (10.1016/j.jaad.2017.09.078) Copyright © 2017 Terms and Conditions

Fig 3 Patient with severe acne vulgaris treated with adapalene/benzoyl peroxide at baseline and week 12. Journal of the American Academy of Dermatology 2018 78, S1-S23.e1DOI: (10.1016/j.jaad.2017.09.078) Copyright © 2017 Terms and Conditions

Fig 4 Action of retinoids on microcomedones (acne vulgaris precursor lesions) and visible lesions. Note the lag time after cessation of retinoid therapy before visible lesions begin to reappear. Reprinted with permission from Thielitz et al.30 Journal of the American Academy of Dermatology 2018 78, S1-S23.e1DOI: (10.1016/j.jaad.2017.09.078) Copyright © 2017 Terms and Conditions

Fig 5 Examples of adult female acne vulgaris. Photos courtesy of Dr Araviiskaia of the Department of Dermatology and Venereal Diseases First Pavlov Medical University of St. Petersburg, St. Petersburg, Russia; Dr Castinahan; Dr Kemeny of the Department of Dermatology and Allergology, University of Szeged; and Dr Troielli. Journal of the American Academy of Dermatology 2018 78, S1-S23.e1DOI: (10.1016/j.jaad.2017.09.078) Copyright © 2017 Terms and Conditions

Fig 6 Atrophic acne scar risk assessment tool.87 Journal of the American Academy of Dermatology 2018 78, S1-S23.e1DOI: (10.1016/j.jaad.2017.09.078) Copyright © 2017 Terms and Conditions

Fig 7 Practical approach to acne management. Journal of the American Academy of Dermatology 2018 78, S1-S23.e1DOI: (10.1016/j.jaad.2017.09.078) Copyright © 2017 Terms and Conditions

Fig 8 Spectrum of postinflammatory hyperpigmentation. BPO, Benzoyl peroxide. Photos courtesy of DermQuest.com, Dr C. L. Goh, and Dr R. Kubba. Copyright © 2006 Galderma S.A. All rights reserved. Journal of the American Academy of Dermatology 2018 78, S1-S23.e1DOI: (10.1016/j.jaad.2017.09.078) Copyright © 2017 Terms and Conditions