Deep brain single optical fiber fluorescence imaging Israel Delarosa BIST Lab

Optogenetics Provides bi-directional control of neurons by introducing Light-sensitive proteins originally adapted from algae and bacteria, into neurons. Ability to target specific cell-types of the neuron and avoid inadvertent stimulation to unrelated neurons. Offers higher spatial and temporal resolution over traditional electrodes used for brain stimulation.

A&B Experimental Set up C Cross Sections D Vertical Path E Rotational Path F Results

Conclusion For successful optogenetic and neuroscience research Accurate location information Effective light delivery mechanism