Histology of cartilage

Histology of cartilage Introduction Modified (solid type) of connective tissue. Forms the skeletal basis of some parts of the body. Avascular E.g. Auricle of the ear, lower part of the nose. Histology of cartilage

Histology of cartilage Components Cells Matrix Chondrocytes Fibers Collagen OR Elastic fibers Ground substance Tissue fluid GAG & proteoglycans Histology of cartilage

Histology of cartilage Chondrocytes Derived - chondroblast Chondroblast - mesenchymal cell Seen in spaces - lacunae Histology of cartilage

Histology of cartilage 3 types of cartilage Hyaline cartilage Elastic cartilage Fibrocartilage Histology of cartilage

Histology of cartilage

Matrix (fibers + ground substances) Type II collagen fibers Proteoglycans, Hyaluronic acid Capsule or territorial matrix Interterritorial matrix Lacunae (tiny spaces in the matrix) Isogenous cell nest / CELL NESTS (offspring of a common parent cell). Histology of cartilage

Histology of cartilage Seen under microscope Histology of cartilage

Hyaline cartilage Fibrous layer Chondrogenic layer Perichondrium Chondroblasts Cell nest Matrix Chondrocyte in lacuna

Hyaline cartilage- magnified Terretorial matrix Interterretorial matrix Chondrocyte in lacuna Cell nest

Histology of cartilage Distribution Costal cartilage Articular cartilage Thyroid, cricoid, arytenoid Tracheal rings Part of nasal septum Epiphyseal plate Histology of cartilage

Elastic cartilage (yellow fibrocartilage) Greater flexibility. Ground substance contains abundance of branching and anastomosing elastic fibres. No isogenous cell nests. Chondrocytes are found in single or in small groups. Histology of cartilage

Histology of cartilage Elastic cartilage Histology of cartilage

Elastic cartilage (microscopic view) Histology of cartilage

Elastic cartilage Fibrous layer Chondrogenic layer Chondroblast Perichondrium Chondroblast Matrix with elastic fibers Chondrocyte in the lacuna

Histology of cartilage Distribution Auricle & lateral part of the external acoustic meatus. Medial part of auditory tube. Histology of cartilage

Histology of cartilage Epiglottis, corniculate, cuneiform, apical part of arytenoid. Histology of cartilage

Histology of cartilage White fibrocartilage It is intermediate between Dense connective tissue and hyaline cartilage (tensile strength) Chondrocytes are found in singles or in rows with bundles of collagen with little matrix. No perichondrium. Bundles of collagen (type1) Histology of cartilage

Histology of cartilage White fibrocartilage Histology of cartilage

White fibrocartilage (microscopic view) Histology of cartilage

White-fibro cartilage Chondrocyte Matrix

Histology of cartilage Distribution Secondary cartilaginous joints intervertebral discs, pubic symphysis. Histology of cartilage

Histology of cartilage Articular discs Histology of cartilage

Histology of cartilage Menisci of the knee joint Histology of cartilage

Histology of cartilage Growth of Cartilage Interstitial Growth ?? Appositional Growth?? Histology of cartilage

Histology of cartilage