Schematic diagram showing upper motor neuron (UMN) and lower motor neuron (LMN) lesions relative to the spinal cord. Schematic diagram showing upper motor.

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Schematic diagram showing upper motor neuron (UMN) and lower motor neuron (LMN) lesions relative to the spinal cord. Schematic diagram showing upper motor neuron (UMN) and lower motor neuron (LMN) lesions relative to the spinal cord. UMN lesions (1) may occur anywhere cranial to the nerve roots that give rise to the nerves involved in the reflex/limb/muscle group in question. They disrupt the descending (inhibitory) axons that originate in the brain and also disrupt ascending pathways conveying sensation and proprioceptive information. LMN lesions may be central (2) or peripheral (3). Lesions in these locations may affect just motor neuron function or may affect both motor neurons and sensory neurons, leading to a loss of sensation as well as paresis/paralysis James Patrick Crilly et al. In Practice 2015;37:490-507 Copyright © British Veterinary Association. All rights reserved.