Where does meniscal damage progress most rapidly

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Where does meniscal damage progress most rapidly Where does meniscal damage progress most rapidly? An analysis using three- dimensional shape models on data from the Osteoarthritis Initiative B. Dube, M.A. Bowes, S.R. Kingsbury, E.M.A. Hensor, S. Muzumdar, P.G. Conaghan Osteoarthritis and Cartilage Volume 26, Issue 1, Pages 62-71 (January 2018) DOI: 10.1016/j.joca.2017.10.012 Copyright © 2017 Terms and Conditions

Fig. 1 Identification of anatomical regions and measurement. Figure A shows the mean shape of the menisci for this group of 86 individuals. Figure B shows the anatomical correspondence points (blue spheres) from the tibia bone shape model which are used to subdivide the tibial plateaus, from which measurements are taken. Figure C shows the anterior (purple), central (light blue) and posterior (dark blue) regions on the lateral and medial tibial plateaus, selected using the correspondence points, and D shows the mean meniscus split into three regions for each meniscus. Figure E shows the correspondence points identified along the outer boundary of the medial tibia. These points are joined into a line, and extruded into a plane in the superior direction, which cuts the meniscus into an inner and outer section. F shows the extruded section. Figure G shows how thickness measures are taken using the underlying correspondence points on the tibia bone. Osteoarthritis and Cartilage 2018 26, 62-71DOI: (10.1016/j.joca.2017.10.012) Copyright © 2017 Terms and Conditions

Fig. 2 Variety of meniscus shapes; examples from the data set and healthy mean shape. Menisci are shown in red, with slight transparency to visualise extrusion beyond tibial bone. Figure A shows the mean medial and lateral meniscus shape from a group of healthy (KL0) knees from the OAI for comparison with cases. B shows a damaged medial meniscus, which is much thinner than the healthy meniscus, the central section is almost all extruded beyond the tibia. C shows both the medial and lateral menisci deformed by a tibial osteophyte (red arrow, posterior medial osteophyte pushing the meniscus anteriorly; black arrow anterior lateral osteophyte pushing the meniscus posteriorly). D shows both menisci are damaged. Osteoarthritis and Cartilage 2018 26, 62-71DOI: (10.1016/j.joca.2017.10.012) Copyright © 2017 Terms and Conditions

Fig. 3 Mean thickness of baseline and 12-month menisci, and difference map. Left hand figures show mean thickness (height above the tibia) at baseline and 12 months, with the colour scale shown below the figures. Measurements were taken as shown in Fig. 1(G). The figure at the right shows the areas which showed significant change at each model correspondence point, as described in the text. Blue represents thinning of the meniscus, and red is thickening. Osteoarthritis and Cartilage 2018 26, 62-71DOI: (10.1016/j.joca.2017.10.012) Copyright © 2017 Terms and Conditions