Volume 126, Issue 1, Pages 42-48 (January 2004) The role of mismatch repair gene defects in the development of adenomas in patients with HNPCC  Andrea E. De Jong, Hans Morreau, Marjo Van Puijenbroek, Paul H.C. Eilers, Juul Wijnen, Fokko M. Nagengast, Gerrit Griffioen, Annemieke Cats, Fred H. Menko, Jan H. Kleibeuker, Hans F.A. Vasen  Gastroenterology  Volume 126, Issue 1, Pages 42-48 (January 2004) DOI: 10.1053/j.gastro.2003.10.043

Figure 1 Cumulative proportion of subjects free of adenoma based on the combined endoscopic findings at first and follow-up colonoscopies. Dashed line, controls; solid line, carriers. Log-rank test; P < 0.0001. Gastroenterology 2004 126, 42-48DOI: (10.1053/j.gastro.2003.10.043)

Figure 2 Distribution of adenomas and carcinomas in the colorectum in the 2 groups. Proximal, colon proximal from the splenic flexure; distal, localized at and distal from the splenic flexure until the rectum. χ2 test. ∗Difference in distribution of adenomas between both groups (P = 0.002). ∗∗Difference in distribution between adenomas and carcinomas in the carrier group (P = 0.007). Gastroenterology 2004 126, 42-48DOI: (10.1053/j.gastro.2003.10.043)