Muscle Development: Nucleating Microtubules at the Nuclear Envelope

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Muscle Development: Nucleating Microtubules at the Nuclear Envelope Daniel A. Starr  Current Biology  Volume 27, Issue 19, Pages R1071-R1073 (October 2017) DOI: 10.1016/j.cub.2017.08.030 Copyright © 2017 Elsevier Ltd Terms and Conditions

Figure 1 Nuclear spreading in developing myotubes. Nuclei (blue) spread apart in a developing myotube using three mechanisms. Nesprin-1/2 functions as a cargo adaptor for kinesin-1 (left inset). MAP7 and kinesin-1 slide antiparallel microtubules apart (center inset). Nesprin-1α recruits pericentriolar material to the nuclear envelope where it nucleates microtubules (right inset). Current Biology 2017 27, R1071-R1073DOI: (10.1016/j.cub.2017.08.030) Copyright © 2017 Elsevier Ltd Terms and Conditions