Effects of melatonin on histomorphology and on the expression of steroid receptors, VEGF, and PCNA in ovaries of pinealectomized female rats Lucrecia.

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Effects of melatonin on histomorphology and on the expression of steroid receptors, VEGF, and PCNA in ovaries of pinealectomized female rats Lucrecia Regina G. Romeu, Ph.D., Eduardo Leme A. da Motta, Ph.D., Carla C. Maganhin, M.S., Celina T.F. Oshima, Ph.D., Marcelle C. Fonseca, Karina F. Barrueco, Ricardo S. Simões, Renata Pellegrino, Edmund C. Baracat, Ph.D., José M. Soares-Junior, Ph.D. Fertility and Sterility Volume 95, Issue 4, Pages 1379-1384 (March 2011) DOI: 10.1016/j.fertnstert.2010.04.042 Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Photomicrographs of histologic sections from adult rat ovaries. Notice the great quantity of interstitial cells in GIII, with higher expression of PCNA than the other groups. Fertility and Sterility 2011 95, 1379-1384DOI: (10.1016/j.fertnstert.2010.04.042) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Histologic sections of representative segments of adult rat ovaries. The purple color indicates positive reaction for VEGF. A large quantity of interstitial cells and remarkably higher VEGF expression are visible in GIII (C) compared with the other images (A = GI; B = GII; and D = GIV). Fertility and Sterility 2011 95, 1379-1384DOI: (10.1016/j.fertnstert.2010.04.042) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions