NovaMouseTM Sherazad Mahomedally Nicole Serago Pooja Shah Advisors:

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Operational Amplifiers

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Presentation transcript:

NovaMouseTM Sherazad Mahomedally Nicole Serago Pooja Shah Advisors: Bob Allen Ben Schnitz

Significance of Mice Increasing use in research Transgenic and Breeding capabilities Miniature size Low maintenance cost

Problem to be Solved No desirable method of measurement Miniature size Difficulty with physiological measurements

Why pulse oximetry? Measure blood oxygen saturation Measure heart rate Monitoring during surgery Research on free ranging mice

Why NovaMouseTM? Survival of mice Reduction of cost Less expensive

Specific Goals To build a pulse oximeter for a mouse: Small size Ability to be wireless Allows movement Accurate Reaching heart rates up to 800 beats per minute

Current Design Nonin Medical, Inc. Pros: Cons: Allows movement For large animals Inaccurate Not wireless http://www.nonin.com/Products/8500V.html

Our Design Reduced hemoglobin vs. oxyhemoglobin DC and pulsatile components Ratio of ratios

Design Specifications Frequency range: 0.1 Hz to 150 Hz Op Amp: 2.3V to 5.5V supply Rechargeable Battery: 4.8V LED: 1.7V supply Gain: 10 Tail dimensions

Circuit Transimpedance Amplifier High Pass Filter Two Pole Low Pass Filter Low Pass Filter

Problems Encountered/ Solutions Found new LED’s with common input voltage of 1.7V Used wrist straps carefully Incompatible red and infrared LED voltage ranges Red LED: 1.8V to 4V Infrared LED: 1V to 1.5V Blown out op amps due to static electricity

Market Potential and Budget Universities, hospitals, and other research facilities 50,000 devices in the year 2004 About 1 million mice are potential targets $5-10 million in sales $100 in expenses to date

Status