Entering into Pathomorphology Entering into Pathomorphology. Morphology reversible and irreversible damage of cells and tissues as.-prof. V. Voloshyn (According to professor Ya.Ya. Bodnar et al.)
Pathomorphology - it is clinical speciality the basic function of which is vitality and posthumous diagnostics of illnesses. Additional functions are: studying of etiology, pathogeny and thanatogeny of the most widespread illnesses, control of clinical diagnostics quality and efficiency of medical process, and also improvement of professional doctors preparation.
Pathomorphology's Methods: macroscopic, microscopic and experimental. To the additional methods belong biological (bacteriological, virologic, serum, haematological, method of tissues cultures), chemical (hystochemical, immunohystochemical, atomic absorptiometry, quantitative analysis, high-quality analysis, biochemical), physical (hystoautoradiography, X-ray examination, ultrasonic diagnostics).
PATHOHYSTOLOGICAL DIAGNOSTICS
Morphology of pathological accumulation of products of matters exchange
Reasons of pathological accumulation of products of matters exchange 1. Pathology of cell. 2.Parafunction transporting systems. 3.Disorders of the endocrine and nervous adjusting of trophism.
Mechanisms of pathological accumulation of products of exchange of matters Infiltration. Decomposition (phanerosis). The disfigured synthesis. Transformation.
Classification of pathological accumulation of products of matters exchange (A) According to predominance of violation of that or other exchange types: a) albumens (proteins) b) lipids c) hydrocarbons d) mineral
According to localization of pathological process: Classification of pathological accumulation of products of matters exchange (B) According to localization of pathological process: a) parenchymatic b) stromal-vascular c) mixed
Depending on influencing of genetic factors: Classification of pathological accumulation of products of matters exchange (C) Depending on influencing of genetic factors: a) innate (congenital). b) acquired.
According to a process expansion: Classification of pathological accumulation of products of matters exchange (D) According to a process expansion: a) ) general b) local.
Parenchymatic disproteinosis Hyaline-dropic Hydropic Cornea (ikhtiosis, keratosis)
Parenchymatic disproteinosis
Stromal-vascular disproteinosis Mucoid swelling. Fibrynoid swelling. Hyalinosis. Amyloidosis
Stromal-vascular disproteinosis
The hyalinosis of valves of heart The hyalinosis of spleen arteries The hyalinosis of valves of heart
Disorders of the fat exchanging (lipidosis) LIPIDOSES Parenchimatic Stromal-vascular Organics Systemic Accumulation os the fat Lose of the fat content miocardium (tiger’s heart) liver (goose liver) kidney Diseases of Hoshe, Niman-Pic, Thea-Sax’s gangliosidosis obesity atherosclerosis Diseases of Dercum, Veber-Krischen Kahexia (depletion)
Parenchymatic lipidosis
Common obesity
Violation of cholesterol exchange
Pathological accumulation of glycogen
The main clinical-morphological manifestations of disorder of hemoglobin pigments exchanging Total Local Hemosiderinum Hemosiderosis Feritinum Feritinaemia Hypotensia Overhepatic Hepatic Subhepatic Bilirubinum Jaundice Melena Haemomelanosis Hematinum Lightphobia Erithema Dermatitis Porferinum Porferia
Haemorragic stroke
Haemosiderosis
Haemochromatosis. Vilson's illness
Icterus
Haematines
Haemomelanosis
Foot gangrene
Melanoma
Adisson illness
Brown atrophia of myocardium
Thank you for your attention! The end.