Schematic of the Cell Cycle of Eukaryotic Cells

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Presentation transcript:

Schematic of the Cell Cycle of Eukaryotic Cells

Cell Cycle Progression

Change in Cyclin Concentration between Mitosis

Eukaryotic DNA Polymerases

Eukaryotic Replication Form

Eukaryotic DNA Polymerases

Domain Structure of Different Eukaryotic DNA Polymerases

The Genome of the SV40 Virus

The Origin Sequence of SV40

Interaction of Large T-antigen with the Origin Sequence

Summary SV40 DNA Replication

Linker Substituition Mutations in ARS1 Origin Sequence

Linker Substituition Mutations in ARS1

Shortening of the A Domain in ARS1

Substitution of B Domains in the ARS1 Origin Sequence

Gel Mobility Shift Assay of ORC-ARS1 Complex

Gel Mobility Shift Assay of Mutant ARS1

Footprinting of the ARS1-ORC Complex

ORC1-related Sequences in Other Organism

ORC2-related Sequences in Various Organism ( A. Thaliana, S. cerevisiae, Humans, C.elegans)

Drosophila Homologs of S. Cerevisiae Proteins DmORC2 DmORC5

OriGNA13 is the Prominent Initiation Site of the AMPD2 Region in Cells 422

OriGNAI3 and Newly detected Origins Co-Map with AT-Rich Regions

Events Leading to Origin Activation in Budding Yeast

The ORC cycle in Different Eukaryotes

Model of DNA Replication of Eukaryotic Chromosomal DNA