HOX A10 and HOX A11 mutation scan in congenital malformations of the female genital tract  Spiros A. Liatsikos, Grigoris F. Grimbizis, Ioannis Georgiou, Nikolaos Papadopoulos, Leandros Lazaros, John N. Bontis, Basil C. Tarlatzis  Reproductive BioMedicine Online  Volume 21, Issue 1, Pages 126-132 (July 2010) DOI: 10.1016/j.rbmo.2010.03.015 Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 1 Single-strand conformation polymorphism analysis revealed a shift in the sequence of HOX A11 F1/R1 PCR product in one sample. As it can be seen, an extra band is produced after the electrophoreses of the product below the arrow, which is not apparent in other samples when compared with each other. Reproductive BioMedicine Online 2010 21, 126-132DOI: (10.1016/j.rbmo.2010.03.015) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

Figure 2 DNA sequencing of the specific PCR product. The double peak (arrow) represents a heterozygotic substitution of a cytosine by a guanine, leading to a 113 C>G (P38R) mutation. The mutation causes the substitution of a proline by an arginine in codon 38. Reproductive BioMedicine Online 2010 21, 126-132DOI: (10.1016/j.rbmo.2010.03.015) Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions