HIV: Clinical manifestations

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Presentation transcript:

HIV: Clinical manifestations Edina H. Moylett, MD, William T. Shearer, MD, PhD Journal of Allergy and Clinical Immunology Volume 110, Issue 1, Pages 3-16 (July 2002) DOI: 10.1067/mai.2002.125978 Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 1 Graphic representation of the global distribution of HIV and AIDS. Figure adapted from the Joint United Nations Programme on HIV-AIDS. (UNAIDS. Global HIV/AIDS and STD Surveillance. Available at www.unaids.org Journal of Allergy and Clinical Immunology 2002 110, 3-16DOI: (10.1067/mai.2002.125978) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 2 Proposed spectrum of clinical and biochemical abnormalities in HIV-associated fat-redistribution syndromes. PI exposure results in hyperlipidemia with primary lipohypertrophy. NRTI exposure results in significant mitochondrial toxicity and resultant lipodystrophy. Journal of Allergy and Clinical Immunology 2002 110, 3-16DOI: (10.1067/mai.2002.125978) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 3 Oral hairy leukoplakia in a young immigrant child with previously undiagnosed HIV infection. This is an unusual clinical manifestation in the pediatric population. Journal of Allergy and Clinical Immunology 2002 110, 3-16DOI: (10.1067/mai.2002.125978) Copyright © 2002 Mosby, Inc. Terms and Conditions

Fig. 4 Severe Candida species esophagitis in an adolescent patient with advanced HIV-AIDS receiving HAART (poor compliance). HSV was also isolated from a biopsy sample on viral culture. Journal of Allergy and Clinical Immunology 2002 110, 3-16DOI: (10.1067/mai.2002.125978) Copyright © 2002 Mosby, Inc. Terms and Conditions