Recent Advances in Bronchoscopic Treatment of Peripheral Lung Cancers

Slides:



Advertisements
Similar presentations
Pulmonary Stereotactic Ablative Radiotherapy:
Advertisements

Debapriya Datta, MD, FCCP, Vanessa Yap, MD  CHEST 
CT and PET imaging in non-small cell lung cancer
Arun C. Nachiappan, MD, Amita Sharma, MBBS, Jo-Anne O
Bronchoscopy-Guided Cooled Radiofrequency Ablation as a Novel Intervention Therapy for Peripheral Lung Cancer Respiration 2015;90: DOI: /
Chun-Ku Chen, Hsiao-Ping Chou, Ming-Huei Sheu 
Intensity modulated radiation therapy for definitive treatment of paraortic relapse in patients with endometrial cancer  Shervin M. Shirvani, MD, Ann.
Abscopal effect in recurrent colorectal cancer treated with carbon-ion radiation therapy: 2 case reports  Daniel K. Ebner, BS, Tadashi Kamada, MD, PhD,
A Cancer That Went Up in Smoke
Squamous Cell Lung Cancer Simulating an Acute Myocardial Infarction
Jeffrey Bradley, MD  Journal of Thoracic Oncology 
Volume 131, Issue 1, Pages (January 2007)
Marked Tumor Response and Fatal Hemoptysis During Radiation for Lung Cancer in a Human Immunodeficiency Virus-Positive Patient Taking Nelfinavir  Christopher.
Chad G. Rusthoven, MD, Christine F. Lauro, MD, Brian D
Image–Guided Radiation Therapy for Non–small Cell Lung Cancer
Stereotactic radiosurgery for lung tumors: preliminary report of a phase I trial  Richard I Whyte, MD, Richard Crownover, MD, PhD, Martin J Murphy, PhD,
Cavitary Lung Disease with Skin Lesions
Pain Control by Image-Guided Radiosurgery for Solitary Spinal Metastasis  Samuel Ryu, MD, Ryan Jin, MD, Jian-Yue Jin, PhD, Qing Chen, PhD, Jack Rock, MD,
J. Wesley King, M.D., Thomas E. Walsh, M.D., F.C.C.P.  CHEST 
A 51-Year-Old Woman With an Increasing Chest Wall Mass Years After Resection of an Early Stage Lung Cancer  Ajay Dhakal, MBBS, Hongbin Chen, MD, PhD,
Use of virtual assisted lung mapping (VAL-MAP), a bronchoscopic multispot dye- marking technique using virtual images, for precise navigation of thoracoscopic.
Preoperative Localization of Lung Nodules With Fiducial Markers: Feasibility and Technical Considerations  Amita Sharma, MD, Shaunagh McDermott, MD, Douglas.
Abscopal Effect of Nivolumab in a Patient with Primary Lung Cancer
Hiren J. Mehta, MD, Tan-Lucien Mohammed, MD, Michael A. Jantz, MD 
Gaetano Rocco, MD, FRCSEd 
Interventional Management of Pleural Infections
The Lung Reporting and Data System (LU-RADS): A Proposal for Computed Tomography Screening  Daria Manos, MD, Jean M. Seely, MD, Jana Taylor, MD, Joy Borgaonkar,
Radiotherapeutic Management of Non–Small Cell Lung Cancer in the Minimal Resource Setting  Danielle Rodin, MD, Surbhi Grover, MD, MPH, Melody J. Xu, MD,
Positron Emission Tomography in Lung Cancer
Technologies for Ablation of Hepatocellular Carcinoma
Intensity-Modulated Radiotherapy After Extrapleural Pneumonectomy in the Combined- Modality Treatment of Malignant Pleural Mesothelioma  Alexander Chi,
Severe Local Toxicity after Lung Stereotactic Body Radiation Therapy: Lesional Abscess Leading to Bronchocutaneous Fistula Requiring Surgical Marsupialization 
Image–Guided Radiation Therapy for Non–small Cell Lung Cancer
David T. Cooke, MD, Dennis J. Zheng, Karen A. Peterson, NP, Royce F
Volume 151, Issue 5, Pages e99-e102 (May 2017)
Details and Difficulties Regarding the New Lung Cancer Staging System
Successful Treatment of Invasive Pulmonary Mucormycosis in an Immunocompromised Patient  Oluwatobi Afolayan, BS, Hannah Copeland, MD, Rachel Hargrove,
Debapriya Datta, MD, FCCP, Vanessa Yap, MD  CHEST 
Bronchopleural Fistula Treated With a Silicone-Covered Bronchial Occlusion Stent  Eun Young Chae, MD, Ji Hoon Shin, MD, Ho-Young Song, MD, Jin-Hyoung Kim,
Stereotactic Ablative Radiotherapy for Centrally Located Early Stage Non–Small-Cell Lung Cancer: What We Have Learned  Joe Y. Chang, MD, PhD, Andrea Bezjak,
Endobronchial ultrasonographically guided transbronchial needle aspiration in mediastinal abscesses  Yen-Fu Chen, MD, Chao-Chi Ho, MD, PhD, Chung-Yu Chen,
Stereotactic radiosurgery for lung tumors: preliminary report of a phase I trial  Richard I Whyte, MD, Richard Crownover, MD, PhD, Martin J Murphy, PhD,
Intraoperative Computed Tomography Navigation During Thoracoscopic Segmentectomy for Small-sized Lung Tumors  Sung Soo Chang, MD, Taku Okamoto, MD, Yoshimasa.
Endobronchial Ultrasonography: Current Status and Future Directions
Follow-Up of Patients after Stereotactic Radiation for Lung Cancer: A Primer for the Nonradiation Oncologist  Kitty Huang, MSc, MDCM, David A. Palma,
Kiran Devisetty, MD, Joseph K. Salama, MD  Journal of Thoracic Oncology 
Technical Advances of Radiation Therapy for Thymic Malignancies
Chest Wall Pain and Rib Fracture after Stereotactic Radiotherapy for Peripheral Non- small Cell Lung Cancer  Jon-Paul J. Voroney, PhD, MD, Andrew Hope,
Gray R. Lyons, MD, PhD, Bradley B. Pua, MD, FSIR 
Volume 148, Issue 5, Pages e142-e147 (November 2015)
Persistent Lobar Atelectasis in a Patient With Chronic Hoarseness
An 82-Year-Old Woman With Left Upper Lobe Atelectasis
Bronchiectasis Complicating Lung Volume Reduction Coil Treatment
A Cancer That Went Up in Smoke
Demonstration of persistent tumor cells 4 weeks after radiofrequency ablation of a pulmonary adenocarcinoma  Stéphane Renaud, Marco Schiavon, MD, Nicola.
Stereotactic Body Radiation Therapy for Primary Lung Cancers >3 Centimeters  John J. Cuaron, MD, Ellen D. Yorke, PhD, Amanda Foster, BA, Meier Hsu, MS,
Brachytherapy for Tracheal Lobular Capillary Haemangioma (LCH)
Matthew Reichert, MD, Eric S. Bensadoun, MD 
Jeffrey Bradley, MD  Journal of Thoracic Oncology 
A 58-Year-Old Woman With Back Pain and an Unusual Diagnosis
Pulmonary Atelectasis after Stereotactic Ablative Radiotherapy for a Central Lung Tumor  Sashendra Senthi, MBChB, FRANZCR, Eric F Ullmann, MD, Suresh.
Percutaneous radiofrequency ablation of clinical stage I non–small cell lung cancer  Takao Hiraki, MD, Hideo Gobara, MD, Hidefumi Mimura, MD, Yusuke Matsui,
Todd J. Carpenter, MD, Kenneth E. Rosenzweig, MD 
Volume 108, Issue 5, Pages (November 1995)
Endotracheal and Endobronchial Metastases in a Patient With Stage I Lung Adenocarcinoma  Zhirong Zhang, MD, Yousheng Mao, MD, Huang Chen, MD, Jingsi Dong,
A and B, Computed tomography (CT) of the chest prior to cabozantinib therapy demonstrated a dominant mass in the left upper lobe (B, black arrow), measuring.
Stereotactic Body Radiotherapy for Central Lung Tumors
Use of Fluoroscopy During Endobronchial Ultrasonography for Transbronchial Lung Biopsies of Peripheral Lung Lesions  Daniel Steinfort, MBBS, Louis Irving,
Volumetric and dosimetric comparison of two delineation guidelines for the radiation treatment of laryngeal squamous cell carcinoma  C. Bondue, S. Racadot,
Justin D. Blasberg, MD, Scott J. Belsley, MD, Gary S
Presentation transcript:

Recent Advances in Bronchoscopic Treatment of Peripheral Lung Cancers Kassem Harris, MD, FCCP, Jonathan Puchalski, MD, FCCP, Daniel Sterman, MD, FCCP  CHEST  Volume 151, Issue 3, Pages 674-685 (March 2017) DOI: 10.1016/j.chest.2016.05.025 Copyright © 2016 The Authors Terms and Conditions

Figure 1 A, Navigational bronchoscopy image showing the bronchial tree with airway (pink) leading to the peripheral lung nodule in the apical segment of the right upper lobe (white arrow). B, Image showing the tip of the guide sheath proximal to the target. The green ball represents the right upper nodule in the apical segment. The red arrow shows the alignment of the guide sheath with the target at a 0.3-cm distance. CHEST 2017 151, 674-685DOI: (10.1016/j.chest.2016.05.025) Copyright © 2016 The Authors Terms and Conditions

Figure 2 CT-assisted transbronchial brachytherapy for small peripheral lung cancer. A, Peripheral lung lesions (adenocarcinoma). B, A dummy source was inserted into the lesion. C, An applicator with a dummy source was stabilized between the pleura and the orifice of a tracheal tube to preserve accurate positioning of the radiation center throughout the procedure. D, CT scan after brachytherapy shows radiation fibrosis without apparent changes in the surrounding lung tissue. (Reprinted with permission from Kobayashi et al.31) CHEST 2017 151, 674-685DOI: (10.1016/j.chest.2016.05.025) Copyright © 2016 The Authors Terms and Conditions

Figure 3 Salvage: postradiotherapy ablation. A, PET and corresponding axial CT scans demonstrate a hypermetabolic lesion (black arrows) within the left upper lobe with surrounding radiation change—a difficult lesion to treat surgically. B, Radiofrequency electrode within target lesion (black arrow). C, PET and corresponding axial CT images after treatment demonstrating cavity in the region of prior ablation with smooth surrounding hypermetabolic rim—corresponding to expected postablation changes (black arrows). (Reprinted with permission from Pua et al.33.) CHEST 2017 151, 674-685DOI: (10.1016/j.chest.2016.05.025) Copyright © 2016 The Authors Terms and Conditions

Figure 4 CyberKnife robotic radiosurgery for early-stage non-small cell lung cancer (NSCLC). A-C, Example of radiation dose distribution in axial, sagittal, and coronal images, respectively, of a chest CT scan for a left peripheral lung cancer. D, Beam configuration. A typical treatment plan for a 13-cm3 NSCLC lesion. Treatment would deliver 60 Gy in three fractions to the 65% isodose level using 60 beams, resulting in a V(15) of 4.6%. (Reprinted with permission from Brown et al.55.) CHEST 2017 151, 674-685DOI: (10.1016/j.chest.2016.05.025) Copyright © 2016 The Authors Terms and Conditions

Figure 5 Cryotherapy for lung cancer. A, Preprocedural (left) and procedural (right) images of a 2-cm primary lung cancer in a patient who was not eligible for surgery show the initial needle placement (arrow). The tip was subsequently advanced to the far tumor margin. B, Image on left was obtained 10 weeks after percutaneous cryotherapy (PCT) and shows resolution of the cavitary effect that developed (not shown), with a residual parenchymal reaction but a minimal underlying soft-tissue component. Image on the right was obtained 6 months after PCT and shows nearly complete resolution of the parenchymal reaction and minimal residual scarring. (Reprinted with permission from Wang et al.57). CHEST 2017 151, 674-685DOI: (10.1016/j.chest.2016.05.025) Copyright © 2016 The Authors Terms and Conditions