Region 9 Collaborative New York Academy of Medicine 3/20/18 Setting the Stage Region 9 Collaborative New York Academy of Medicine 3/20/18

National Organ Donation Trends in 2017 3.1% Deceased Donors Recovered 3.7% Deceased Organs Transplanted 3.5.% Living Donors

UNOS Regions

U.S. Region 9 Donors Recovered Organs Recovered Organs Transplanted OTPD 2016 9,971 35,361 30,497 3.059 2017 10,284 36,413 31,614 3.074 % Change 3.1% 3.0% 3.7% 0.5% Region 9  Donors Recovered Organs Recovered Organs Transplanted OTPD 2016 443 1,366 1,195 2.698 2017 458 1,457 1,278 2.790 % Change 3.4% 6.7% 6.9%

Deceased Donors by Type and UNOS Region

Closing the Gap Average of 7.9 patients waiting per donor

Closing the Gap Average of 10.6 patients waiting per donor

Variation in Region 9 Performance

Organ Donor Conversion Rate CMS Eligible Death: Individual </= 75 years who is declared brain dead and does not exhibit any of the following indications: tuberculosis, HIV, Creutzfeldt-Jacob Disease, herpetic septicemia, rabies, reactive hepatitis B surface antigen, any retrovirus infection, active malignant neoplasms, Hodgkin disease, multiple myeloma, leukemia, miscellaneous carcinomas, aplastic anemia, agranulocytosis, fungal and viral encephalitis, gangrene of bowel, extreme immaturity, or positive serological or viral culture findings for HIV. Eligible Donor: A donor whose death met the definition of eligible death. CMS Conversion Rate = Eligible Donors/Eligible Deaths Additional Potential/Donors: Individuals who are declared brain dead and >/= 76 years, and DCD Donors;

Donor Conversion Rates 347 Donors/ 573 Deaths (61% Conversion Rate) 458 Donors/1,272 Estimated Deaths (36% Conversion Rate) Organ Transplants Donors CMS Eligible Deaths Referrals to OPO In Hospital Deaths CMS eligible deaths and total actual donors from 2017 UNOS data. Estimated potential deaths estimated using 1/1/17-7/31/17 actual potential conversion rate for hospital systems with transplant centers in NY.

OPPORTUNITIES TO INCREASE DONATIONS Registry Enrollments

OPPORTUNITIES TO INCREASE DONATIONS USA January 2016 - December 2016 January 2017 - December 2017 Total Donors 9,971 10,287 Organs Transplanted 30,409 31,527 OTPD 3.05 3.06 Consented Eligibles 75.7 73.7 Collaborative Conversion Rate 77.0% 74.4% Region 9 January 2016 - December 2016 January 2017 - December 2017 Total Donors 443 458 Organs Transplanted 1,186 1,269 OTPD 2.68 2.77 Consented Eligibles 60.1% 61.6% Collaborative Conversion Rate 66.7% 67.0%

OPPORTUNITIES TO INCREASE DONATIONS Organs Transplanted per Donor Organs transplanted per donor (OTPD): Total number of organs transplanted divided by the number of donors, not limited to eligible deaths.

Improvements in Registry Enrollments, Conversion Rates & Organs Transplanted per Donor will help Close the Gap Waitlist 3/2018 Hearts Lung Kidneys Livers Other 370 67 7,897 1,081 349

Region 9 Collaborative Goals Increase Eligible Donor Conversion Rate: Baseline 61.6% Increase Total Donor Conversion Rate: Baseline 36% Increase Transplanted Organs per Donor: Baseline 2.77