Real-time BioPharmaceutical R&D Andy Palmer, SVP Operations

Knowledge Capture & Search Effective/Efficient R&D is doing the right experiments & Capturing the findings from every experiment as an Asset…in Real Time Finding Leads Developing Assays Business Operations Making Libraries Partner Collaboration Process Automation Knowledge Capture & Search Predictive Modeling Web services Activity LIMS Compounds Knowledge

InfiNet Knowledge Platform:Plug & Play Web Service Architecture Integrates Biopharmaceutical R&D Knowledge Easy-to-use science applications InfiNet Knowledge Platform: 100s reusable web services Integrated backend of plug & play solutions Experiment & design Enumeration & descriptors Lab & analytical data Compound & activity data Database & documents Analysis & visualization

Service Oriented Architecture: Maximize IT Agility for Drug Discovery Web Services Rampant reuse Integrated view of information Optimize build-buy options through plug n’play of software assets Traditional Approach Limited reuse of software assets Silos of information Constrained build-buy options

Service oriented architecture enables composite applications User Dashboards Any application Any company Any platform Any data source In-house Commercial Internal Partners .Net J2EE Docs DBMS

Integrated, Real Time Scientific Information Search & Analysis Discovery data available across projects, discipline, time Semantically rich data model Data curated, controlled, QC’d by informatics with scientists No data silos Purchasing Analytical Bio-activity Cross-resource chemical biology search and exploration Inventory Literature Synthesis

Guides capture key processes – Hit Picking

Guides capture key processes - SAR

Spotfire at Infinity – Guides capture processes