Chronic cutaneous disseminated Trichosporon asahii infection in a nonimmunocompromised patient Sung-Han Kim, MD, Dong-Hyun Kim, MD, Sei-Ick Joo, PhD,

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Presentation transcript:

Chronic cutaneous disseminated Trichosporon asahii infection in a nonimmunocompromised patient Sung-Han Kim, MD, Dong-Hyun Kim, MD, Sei-Ick Joo, PhD, Jae-Il Yoo, PhD, Hong-Bin Kim, MD, Nam-Joong Kim, MD, Yeong Seon Lee, PhD, Myoung-don Oh, MD, Eui-Chong Kim, MD, Hee Chul Eun, MD, Kang-Won Choe, MD Journal of the American Academy of Dermatology Volume 59, Issue 2, Pages S37-S39 (August 2008) DOI: 10.1016/j.jaad.2007.08.017 Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Photographs of erythematous, scaly, infiltrating plaques of 49-year-old woman on face (A) and trunk and extremities (B). Skin biopsy specimen revealed chronic granulomatous inflammation with yeastlike organism identified as Trichosporon asahii. Skin lesions on face (C) and trunk and extremities (D) improved gradually after 3 months of voriconazole therapy. No fungal organism was observed and T asahii was not cultured from skin biopsy specimen 1 month after voriconazole therapy. Journal of the American Academy of Dermatology 2008 59, S37-S39DOI: (10.1016/j.jaad.2007.08.017) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 A, Section of skin biopsy specimen showing chronic granulomatous inflammation. (Hematoxylin-eosin stain; original magnification: ×200.) B, There are fungal spores in granuloma. (Gomori methenamine silver stain; original magnification: ×400.) Journal of the American Academy of Dermatology 2008 59, S37-S39DOI: (10.1016/j.jaad.2007.08.017) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions