Evaluation and Management of Amenorrhea Bryan McIver, M.B., M.R.C.P.(U.K.), Ph.D., Susan A. Romanski, M.D., Todd B. Nippoldt, M.D. Mayo Clinic Proceedings Volume 72, Issue 12, Pages 1161-1169 (December 1997) DOI: 10.4065/72.12.1161 Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions
Fig. 1 Suggested algorithm for investigation of secondary amenorrhea. The progestin challenge and cyclic estrogen/progestin challenge may be unnecessary in certain clinical circumstances, and measurement of estradiol, LH, and FSH is often substituted. Patients in the diagnostic groups represented in this algorithm may need further appropriate assessment and management of underlying problem. CAH = congenital adrenal hyperplasia; FSH follicle-stimulating hormone; LH = luteinizing hormone; LH.FSH = LH to FSH ratio; PCOS = polycystic ovarian syndrome. Mayo Clinic Proceedings 1997 72, 1161-1169DOI: (10.4065/72.12.1161) Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions