Pathophysiology of the metabolic syndrome

Slides:

Advertisements

Similar presentations

Targets of Immune Regeneration in Rheumatoid Arthritis

Advertisements

Copyright © 2003 American Medical Association. All rights reserved.

Stefano Caccavale, MD, Eleonora Ruocco, MD, PhD Clinics in Dermatology

From: Narrative Review: The Emerging Clinical Implications of the Role of Aldosterone in the Metabolic Syndrome and Resistant Hypertension Ann Intern Med.

Psoriasis and the metabolic syndrome

Ludwik Fleck ( ) and his contribution to dermatology

Non-alcoholic fatty liver disease and cardiovascular risk: Pathophysiological mechanisms and implications Sven M. Francque, Denise van der Graaff, Wilhelmus.

The Correlation Between Metabolic Syndrome and Prostatic Diseases

Volume 153, Issue 3, Pages e7 (September 2017)

Bart Staels, PhD The American Journal of Medicine

Laurent L'homme, PhD, David Dombrowicz, PhD

Prevention of ischemia-reperfusion injury in cardiac surgery: Therapeutic strategies targeting signaling pathways Kay Maeda, MD, PhD, Marc Ruel, MD,

Inositol as putative integrative treatment for PCOS

Ischemic cardiovascular involvement in psoriasis: A systematic review

Vascular biology of metabolic syndrome

Chlamydophila pneumoniae

The role of viruses in acute exacerbations of asthma

Acanthosis nigricans and the metabolic syndrome

Volume 57, Issue 3, Pages (March 2010)

Targets of Immune Regeneration in Rheumatoid Arthritis

Ketamine and depression

From mesothelioma to cardiovascular protection via the phosphoinositide-3 kinase pathway: A new vista in cardiothoracic surgery Igor E. Konstantinov,

JAK inhibitors in dermatology: The promise of a new drug class

Targets of Immune Regeneration in Rheumatoid Arthritis

Oxidative stress in autism

Thomas McFadyen, MB, ChB, Stewart Douglas, FRCP (Glas)

Ischemic cardiovascular involvement in psoriasis: A systematic review

An adventure in dermatology: A personal history

Volume 92, Issue 5, Pages (March 1998)

Albert Szent-Györgyi ( ): The scientist who discovered vitamin C

Andrew Blauvelt, Mark G. Lebwohl, Robert Bissonnette

TNF-α–induced protein 3 (A20): The immunological rheostat

Oxidative stress and gene expression in sepsis

Regarding “Prospective evaluation of postimplantation syndrome evolution on patient outcomes after endovascular aneurysm repair for abdominal aortic aneurysm”

Alopecia and the metabolic syndrome

Inhibition of mammalian target of rapamycin: Two goals with one shot?

Cutaneous manifestations of diabetes mellitus and the metabolic syndrome Ayse Serap Karadag, MD, Emin Ozlu, MD, Michael Joseph Lavery, MB, BCh, BAO, MRCP.

The paradox of neuronal insulin action and resistance in the development of aging- associated diseases Sophie M. Steculorum, Maite Solas, Jens C. Brüning

William T. Mahle, MD, Emilia Matthews, MS, Kirk R. Kanter, MD, Brian E

Volume 76, Issue 11, Pages (December 2009)

Volume 71, Issue 11, Pages (June 2007)

Estrogen Receptors and the Metabolic Network

Reducing lipids for CV protection in CKD patients—current evidence

Endothelial Cell Injury in Cardiovascular Surgery: The Systemic Inflammatory Response1 Edward M Boyle, MD, Timothy H Pohlman, MD, Marion C Johnson, MD,

Konstantinos G. Michalakis, M.D., James H. Segars, M.D.

Roles of fibrinolytic system components in the nervous system

Catherine J. Hunter, Isabelle G. De Plaen Pathophysiology

Herbert Tilg, Gökhan S. Hotamisligil Gastroenterology

Autoimmune skin diseases and the metabolic syndrome

Charles Hilton Fagge ( ): an early skin physician in London

Charles E. Reed, MD, Hirohito Kita, MD

Interleukin-6 participation in pathology of ocular diseases

Banking on ATM as a new target in metabolic syndrome

Antibiotic De-Escalation

Atopic dermatitis and the metabolic syndrome

Stefania Jablonska, MD, PhD, Tomasz F. Mroczkowski, MD, PhD

Craig S. Stump, MD, PhD, Marc T. Hamilton, PhD, James R. Sowers, MD

Renin–angiotensin system blockade and diabetes: moving the adipose organ from the periphery to the center Oliver Lenz, Alessia Fornoni Kidney International

Ann Marie Schmidt, Kathryn J. Moore Cell Metabolism

Heme Oxygenase 1: Does It Have a Role in Renal Cytoprotection?

Targeting TNF-α: A novel therapeutic approach for asthma

Claus Bachert, MD, PhD, Luo Zhang, MD, Phillippe Gevaert, MD

Volume 58, Issue 4, Pages (April 2013)

Aortic Root Abscess in a Patient with Marfan's Syndrome

P.E. Vlisides, M.S. Avidan, G.A. Mashour

Role reversal: Brain insulin and liver STAT3

Wernicke Encephalopathy—Clinical Pearls

Primary prevention of asthma and allergy

Airway smooth muscle: A modulator of airway remodeling in asthma

Christian Rask-Madsen, George L. King Cell Metabolism

Presentation transcript:

Pathophysiology of the metabolic syndrome Emma McCracken, MRCP (UK), Monica Monaghan, MBBCh, BAO, BSc, PhD, MRCP (UK), Shiva Sreenivasan, FRCP Edin, FRCP Clinics in Dermatology Volume 36, Issue 1, Pages 14-20 (January 2018) DOI: 10.1016/j.clindermatol.2017.09.004 Copyright © 2017 Terms and Conditions

Fig. 1 Schematic diagram of the mechanism of action of insulin on intracellular signaling pathways. GLUT4, glucose transporter 4 (an insulin transporter regulated by insulin); GSK3, glycogen synthase kinase 3; PI3K, phosphoinositide 3-kinase; PKA, protein kinase A. Clinics in Dermatology 2018 36, 14-20DOI: (10.1016/j.clindermatol.2017.09.004) Copyright © 2017 Terms and Conditions

Fig. 2 NADPH Nicotinamide adenine dinucleotide phosphate; IL-6 Interleukin-6; TNF-α Tumour necrosis factor alpha; PAI-1 Plasminogen activator inhibitor-1; OxLDL Oxidized low density lipoprotein. Schematic diagram of the role of inflammatory and oxidative mediators in the pathogenesis of atherosclerosis in the metabolic syndrome. Clinics in Dermatology 2018 36, 14-20DOI: (10.1016/j.clindermatol.2017.09.004) Copyright © 2017 Terms and Conditions