The obesity hypoventilation syndrome

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Presentation transcript:

The obesity hypoventilation syndrome Amy L. Olson, MD, Clifford Zwillich, MD, MACP The American Journal of Medicine Volume 118, Issue 9, Pages 948-956 (September 2005) DOI: 10.1016/j.amjmed.2005.03.042 Copyright © 2005 Elsevier Inc. Terms and Conditions

Figure 1 The possible interactions among impaired respiratory mechanics, abnormal ventilatory drive, sleep-disordered breathing, and neurohormonal insensitivity to leptin that lead to sustained daytime hypercapnia in obese patients. OSAHS, obstructive sleep apnea- hypopnea syndrome; SHVS, sleep hypoventilation syndrome. The American Journal of Medicine 2005 118, 948-956DOI: (10.1016/j.amjmed.2005.03.042) Copyright © 2005 Elsevier Inc. Terms and Conditions

Figure 2 The vicious cycle of obesity hypoventilation syndrome (see text for further explanation). OHS, obesity hypoventilation syndrome; OSAHS, obstructive sleep apnea-hypopnea syndrome. The American Journal of Medicine 2005 118, 948-956DOI: (10.1016/j.amjmed.2005.03.042) Copyright © 2005 Elsevier Inc. Terms and Conditions