} Spcdc25 G2/M Cell cycle iPA (low) Lateral roots Development IAA (high) Ethylene signalling Small isodiametric cells in RAM Cellular architecture Fig. 7. Cross talk between Spcdc25, hormonal signalling and development Spcdc25 depletes and replaces cytokinins at the G2/M transition of the cell cycle (Orchard et al., 2005), depletes iPA and raises IAA to promote lateral root formation and stimulates ethylene signalling to promote small isodiametric cells in cortex and stele of primary roots (data reported here). Figure 7 Spadafora et al.