Figure 2 Exosome composition Figure 2 | Exosome composition. Schematic representation of exosomes and examples of their molecular cargos. AGO2, Argonaute 2; ALIX, ALG-2-interacting protein X (also known as programmed cell death 6-interacting protein); GAPDH, glyceraldehyde-3-phosphate dehydrogenase; HSP90, heat shock protein 90; lncRNA, long noncoding RNA; MHC, major histocompatibility complex class; RABs, Ras-related proteins; TSG101, tumour susceptibility gene 101. Szabo, G. & Momen-Heravi, F. (2017) Extracellular vesicles in liver disease and potential as biomarkers and therapeutic targets Nat. Rev. Gastroenterol. Hepatol. doi:10.1038/nrgastro.2017.71