The role of metabolic surgery in the management of obesity and t2dm

Obesity Management: Precepts vs Myths

What Is Obesity?

Why Obesity Is a Disease

Precepts of Obesity

Precepts of Obesity (cont)

Combinations of Therapies Are Generally Required for Effective Obesity Management

Mechanisms of Bariatric Surgery

Barriers to Obesity Care

MARS

Obesity As A cardiometabolic risk factor

Medical Complications of Obesity

Medical Complications of Obesity (cont)

Mechanisms Driving Obesity-Related Complication

Pathophysiology: Obesity and T2DM

Obesity and the regulation of energy metabolism

Weight and Energy Balance: Historical Perspective

Weight and Energy Balance: Current Perspective

Obesity: Imbalance of Energy Regulation

Feedback Regulation of Energy Metabolism

Environmental Drivers to Obesity

Overall Strategy for the Treatment of Obesity*

Overall Strategy for the Treatment of Obesity (cont)*

Average Effectiveness of Obesity Treatments: SOS Study

Weight Loss Surgery Improves T2DM

Potential Mechanisms Contributing to Improved Glycemia After Bariatric Surgery

BARIATRIC SURGERY AND THE TREATMENT OF OBESITY

Types of Weight Loss Surgery

Altering the "Set Point" With Weight Loss Surgery

RYGB Induces System-Wide Physiological Changes

Mechanisms of Bariatric Surgery

Prevention of T2DM with Bariatric Surgery vs Control: SOS Study

Bariatric Surgery vs Intensive Medical Therapy for T2DM: STAMPEDE Trial

Clinical Indications for Bariatric Surgery

Obesity and t2dm: the global perspective

Trends in the Prevalence of Diabetes in Asian Countries

Algorithm for the Treatment of T2DM as Endorsed by International Diabetes Organizations

Obesity-Related Metabolic Diseases: Consider Full Spectrum of Therapies

Use of Bariatric Surgery Worldwide

Conclusions

Conclusions (cont)

Abbreviations