Metabolic Energy
Metabolic Energy
Metabolic Energy
Metabolic Energy
∆G = ∆G°’ + RTln([B]b/[A]a) For aA + cC ⇄ bB + dD Metabolic Energy For aA ⇄ bB ∆G = ∆G°’ + RTln([B]b/[A]a) For aA + cC ⇄ bB + dD ∆G = ∆G°’ + RTln{([B]b[D]d)/([A]a[C]c)} ∆G = ∆G°’ + RTln({Products}/{Reactants})
if ΔG is negative, A->B is favored Metabolic Energy For A <=> B if ΔG is negative, A->B is favored if ΔG is positive, B-> A is favored if ΔG is 0, B-> A and A-> B are equally favored At ΔG = 0, the system is at equilibrium
Creatine + ATP <=> Creatine Phosphate + ADP Metabolic Energy Muscle Energy Creatine Kinase Creatine + ATP <=> Creatine Phosphate + ADP ΔG0' = +12 kJ/mol
Metabolic Energy
Metabolic Energy
Metabolic Energy
Metabolic Energy Nicotinamide Dinucleotide Adenine
Metabolic Energy Coupled Reactions Glucose + Pi <=> Glucose-6-Phosphate ΔG°’ = +14 kJ/mol Glucose + ATP <=> Glucose-6-Phosphate ΔG°’ = -16.5 kJ/mol
Metabolic Pathways
Metabolic Pathways
Metabolic Pathways
Metabolic Pathways
ΔG°’ Values of Hydrolysis (kJ/mol) Metabolic Pathways ΔG°’ Values of Hydrolysis (kJ/mol) PEP = -61.9 1,3 BPG = -49.4 Creatine Phosphate = -43.1 ATP to ADP = -30.5 G1P = -20.9 Pyrophosphate = -19.3