Synthesis and Design of Novel Electro-Active, Site-Isolated Nanostructures Chinessa Adkins and Eva Harth*, Department of Chemistry, Vanderbilt University, Nashville, TN, 37235 Nanoparticle through Intramolecular chain Collapse process: 5-7 nm ‘Organic Quantum Dot’ ABA Block Copolymer We present the synthesis of polymeric nanoparticles from single ABA type block copolymers in an intramolecular-chain process to result 3-D architectures that confine a single chain of conducting copolymers. ABA triblock copolymers were prepared from conducting polymers such as fluorene homopolymers and fluorene/thiophene copolymers designed as telechelic macroinitiators to facilitate nitroxide mediated living free radical polymerization methods. ABA Block Copolymer The photoluminescence measurements illustrates the influence of the molecular weight of the A block to be crucial for the site-isolation of the embedded conducting polymer block in the resulting nanoparticles with increased quantum efficiencies of 6 %.