Osimertinib-Induced Interstitial Lung Disease Presenting as Eosinophilic Pneumonia Hiroaki Tachi, MD, Toshihiro Shiozawa, MD, Chio Sakai, MD, Mariko Kasuga,

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Osimertinib-Induced Interstitial Lung Disease Presenting as Eosinophilic Pneumonia Hiroaki Tachi, MD, Toshihiro Shiozawa, MD, Chio Sakai, MD, Mariko Kasuga, MD, Kensuke Nakazawa, MD, Yuko Morishima, MD, Hiroaki Satoh, MD, Nobuyuki Hizawa, MD Journal of Thoracic Oncology Volume 12, Issue 8, Pages e118-e120 (August 2017) DOI: 10.1016/j.jtho.2017.03.022 Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

Figure 1 Chest computed tomography scan, before starting osimertinib treatment (A) and at the onset of interstitial lung disease (B). The interlobular septal thickening and bilateral pleural effusion appeared. Multiple lung nodules had significantly decreased in size. Journal of Thoracic Oncology 2017 12, e118-e120DOI: (10.1016/j.jtho.2017.03.022) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions

Figure 2 Representative photographs from bronchoalveolar lavage fluid (A), and transbronchial lung biopsy (B). (A) Total cell count increased with eosinophil predominance. (B) A slight infiltration of eosinophils was observed in the alveolar septal wall. Journal of Thoracic Oncology 2017 12, e118-e120DOI: (10.1016/j.jtho.2017.03.022) Copyright © 2017 International Association for the Study of Lung Cancer Terms and Conditions