Mapping of Pelvic Lymph Node Metastases in Prostate Cancer

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Presentation transcript:

Mapping of Pelvic Lymph Node Metastases in Prostate Cancer Steven Joniau, Laura Van den Bergh, Evelyne Lerut, Christophe M. Deroose, Karin Haustermans, Raymond Oyen, Tom Budiharto, Filip Ameye, Kris Bogaerts, Hein Van Poppel European Urology Volume 63, Issue 3, Pages 450-458 (March 2013) DOI: 10.1016/j.eururo.2012.06.057 Copyright © 2012 European Association of Urology Terms and Conditions

Fig. 1 (a) Sentinel node (SN) procedure in a prostate cancer patient: planar and single-photon emission computed tomography (SPECT) imaging with lead shielding of the prostate, 2h after transrectally injecting 120 MBq of technetium-99m nanocolloid. (b) To facilitate anatomic localization of the SNs, SPECT images were fused with the pelvic staging computed tomography scan. European Urology 2013 63, 450-458DOI: (10.1016/j.eururo.2012.06.057) Copyright © 2012 European Association of Urology Terms and Conditions

Fig. 2 (a) Sentinel nodes were isolated and mapped separately on a standardized lymph node (LN) template. (b) Lymphadenectomy specimens were laid out on a second LN map. European Urology 2013 63, 450-458DOI: (10.1016/j.eururo.2012.06.057) Copyright © 2012 European Association of Urology Terms and Conditions

Fig. 3 (a) Intraoperative picture illustrating superextended lymph node dissection that was performed in all patients; (b) external iliac region (blue), obturator fossa region (green), internal iliac region (yellow), common iliac region (purple), and presacral region (red). European Urology 2013 63, 450-458DOI: (10.1016/j.eururo.2012.06.057) Copyright © 2012 European Association of Urology Terms and Conditions

Fig. 4 (a) Number of sentinel nodes (SNs) scintigraphically detected per region and (b) number of SNs removed per region. Dimensions of the circles correlate with the numbers. European Urology 2013 63, 450-458DOI: (10.1016/j.eururo.2012.06.057) Copyright © 2012 European Association of Urology Terms and Conditions

Fig. 5 (a) Number of positive lymph nodes (LN+) per region and (b) percentage of LN+ of the total number of removed lymph nodes per region in 74 patients. Dimensions of the circles correlate with the numbers. European Urology 2013 63, 450-458DOI: (10.1016/j.eururo.2012.06.057) Copyright © 2012 European Association of Urology Terms and Conditions